发明申请
US20090087866A1 HUMAN T2R RECEPTORS FOR RANITIDINE, STRYCHNINE AND DENATONIUM AND RELATED ASSAYS FOR IDENTIFYING HUMAN BITTER TASTE MODULATORS
有权
人类T2R受体的RANITIDINE，STRYCHNINE和DENATONIUM及相关测定用于鉴定人体双歧杆菌调味剂
- 专利标题： HUMAN T2R RECEPTORS FOR RANITIDINE, STRYCHNINE AND DENATONIUM AND RELATED ASSAYS FOR IDENTIFYING HUMAN BITTER TASTE MODULATORS
- 专利标题（中）： 人类T2R受体的RANITIDINE，STRYCHNINE和DENATONIUM及相关测定用于鉴定人体双歧杆菌调味剂
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申请号： US12166980申请日： 2008-07-02
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公开(公告)号： US20090087866A1公开(公告)日： 2009-04-02
- 发明人: Xiaodong LI , Hong Xu , Huixian Tang , Qing Li
- 申请人： Xiaodong LI , Hong Xu , Huixian Tang , Qing Li
- 主分类号： G01N33/567
- IPC分类号： G01N33/567
摘要：
The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter ligands, i.e., acetaminophen, ranitidine, strychnine and denatonium. The present invention further relates to the use of these receptors in assays for identifying ligands that modulate the activation of these taste receptors and which may be used as additives in foods, beverages and medicinals for modifying (blocking) T2R-associated bitter taste.
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