发明申请
- 专利标题: COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS
- 专利标题(中): 作为蛋白激酶抑制剂的化合物和组合物
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申请号: US11814912申请日: 2006-01-19
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公开(公告)号: US20090105250A1公开(公告)日: 2009-04-23
- 发明人: Taebo Sim , Nathanael Schiander Gray , Hyun Soo Lee , Yi Liu , Pingda Ren , Shuli You , Qiong Zhang , Qiang Ding , Xia Wang , Songchun Jiang , Pamela A. Albaugh
- 申请人: Taebo Sim , Nathanael Schiander Gray , Hyun Soo Lee , Yi Liu , Pingda Ren , Shuli You , Qiong Zhang , Qiang Ding , Xia Wang , Songchun Jiang , Pamela A. Albaugh
- 申请人地址: BM BM Hamilton
- 专利权人: IRM LLC
- 当前专利权人: IRM LLC
- 当前专利权人地址: BM BM Hamilton
- 国际申请: PCT/US06/02266 WO 20060119
- 主分类号: A61K31/427
- IPC分类号: A61K31/427 ; C07D277/56 ; C07D417/14 ; C07D417/12 ; A61K31/454 ; A61K31/506 ; A61K31/5377 ; A61K31/426
摘要:
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, Bcr-Abl, FGFR3, PDGFRβ and b-Raf kinases.
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