发明申请
US20090105258A1 NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
有权
新化合物，其异构体，或其药学上可接受的盐作为VANILLOID受体拮抗剂; 和含有它们的药物组合物
- 专利标题： NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
- 专利标题（中）： 新化合物，其异构体，或其药学上可接受的盐作为VANILLOID受体拮抗剂; 和含有它们的药物组合物
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申请号： US11909136申请日： 2006-03-15
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公开(公告)号： US20090105258A1公开(公告)日： 2009-04-23
- 发明人: Hee-Doo Kim , Young-Ger Suh , Hyeung-Geun Park , Uh Taek Oh , Seol Rin Park , Joo Hyun Kim , Mi Jung Jang , Young-Ho Park , Song Seok Shin , Sun-Young Kim , Jin Kwan Kim , Yeon Su Jeong , Ki-Wha Lee , Jin Kyu Choi , Kyung Min Lim , Hyun Ju Koh , Joo Hyun Moh , Sung-II Kim , Byoung Young Woo
- 申请人： Hee-Doo Kim , Young-Ger Suh , Hyeung-Geun Park , Uh Taek Oh , Seol Rin Park , Joo Hyun Kim , Mi Jung Jang , Young-Ho Park , Song Seok Shin , Sun-Young Kim , Jin Kwan Kim , Yeon Su Jeong , Ki-Wha Lee , Jin Kyu Choi , Kyung Min Lim , Hyun Ju Koh , Joo Hyun Moh , Sung-II Kim , Byoung Young Woo
- 申请人地址： KR Seoul
- 专利权人： AMOREPACIFIC CORPORATION
- 当前专利权人： AMOREPACIFIC CORPORATION
- 当前专利权人地址： KR Seoul
- 优先权： KR10-2005-0022986 20050319
- 国际申请： PCT/KR06/00929 WO 20060315
- 主分类号： A61K31/5375
- IPC分类号： A61K31/5375 ; C07C275/24 ; A61P1/02 ; A61K31/18 ; A61K31/165 ; C07C233/40 ; C07D295/145
摘要：
This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salt thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRRPV1) antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve injury, skin disorder, urinary bladder hypersensitiveness, irritable bowel syndrome, fecal urgency, a respiratory disorder, irritation of skin, eye or mucous membrane, stomach-duodenal ulcer, inflammatory diseases, ear disease, and heart disease.
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