发明申请
- 专利标题: NOVEL IMMUNOTHERAPY AGAINST NEURONAL AND BRAIN TUMORS
- 专利标题(中): 对神经和脑肿瘤的新型免疫治疗
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申请号: US12180170申请日: 2008-07-25
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公开(公告)号: US20090123489A1公开(公告)日: 2009-05-14
- 发明人: Toni WEINSCHENK , Oliver Schoor , Claudia Trautwein , Norbert Hilf , Steffen Walter , Harpreet Singh
- 申请人: Toni WEINSCHENK , Oliver Schoor , Claudia Trautwein , Norbert Hilf , Steffen Walter , Harpreet Singh
- 申请人地址: DE Tuebingen
- 专利权人: Immatics Biotechnologies GmhH
- 当前专利权人: Immatics Biotechnologies GmhH
- 当前专利权人地址: DE Tuebingen
- 优先权: EP07014797.0 20070727; EP08005889.4 20080327
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; C07K7/06 ; C07K7/08 ; C07H21/00 ; A61P37/04 ; C12N15/64 ; A61K38/08 ; C12N5/06
摘要:
The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to 11 novel peptide sequences and their variants derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
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