发明申请
US20090131434A1 Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
有权
11-β-羟基类固醇脱氢酶1型酶的抑制剂
- 专利标题： Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
- 专利标题（中）： 11-β-羟基类固醇脱氢酶1型酶的抑制剂
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申请号： US12355909申请日： 2009-01-19
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公开(公告)号： US20090131434A1公开(公告)日： 2009-05-21
- 发明人: Michael E. Brune , Peer B. Jacobson , James T. Link , Jyoti R. Patel , Jeffrey J. Rohde , Qi Shuai , Martin Winn , Vince S. Yeh , Hong Yong
- 申请人： Michael E. Brune , Peer B. Jacobson , James T. Link , Jyoti R. Patel , Jeffrey J. Rohde , Qi Shuai , Martin Winn , Vince S. Yeh , Hong Yong
- 申请人地址： US IL Abbott Park
- 专利权人： ABBOTT LABORATORIES
- 当前专利权人： ABBOTT LABORATORIES
- 当前专利权人地址： US IL Abbott Park
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; C07C233/01 ; C07D413/02 ; A61P3/10 ; A61K31/16
摘要：
The present invention relates to compounds which are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action.
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