Invention Application
US20090137548A1 1,3-Oxazolidin-2-One Derivatives Useful as Cetp Inhibitors
有权
可用作Cetp抑制剂的1,3-恶唑烷-2-酮衍生物
- Patent Title: 1,3-Oxazolidin-2-One Derivatives Useful as Cetp Inhibitors
- Patent Title (中): 可用作Cetp抑制剂的1,3-恶唑烷-2-酮衍生物
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Application No.: US12087290Application Date: 2006-12-29
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Publication No.: US20090137548A1Publication Date: 2009-05-28
- Inventor: Amjad Ali , Zhijian Lu , Peter J. Sinclair , Yi-Heng Chen , Cameron J. Smith , Hong Li
- Applicant: Amjad Ali , Zhijian Lu , Peter J. Sinclair , Yi-Heng Chen , Cameron J. Smith , Hong Li
- International Application: PCT/US2006/049494 WO 20061229
- Main IPC: C07D263/20
- IPC: C07D263/20 ; A61K31/421 ; A61K31/454 ; A61K31/427 ; C07D413/10 ; C07D417/10 ; A61P9/10
Abstract:
Compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. The compounds have 3 cyclic groups connected by single bonds, as for example triphenyl, which are attached directly to the ring of formula I or attached at the position B.
Public/Granted literature
- US07915271B2 1,3-oxazolidin-2-one derivatives useful as CETP inhibitors Public/Granted day:2011-03-29
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