发明申请
- 专利标题: MONOCLONAL ANTIBODIES AGAINST ORTHOPOXVIRUSES
- 专利标题(中): 抗逆转录病毒的单克隆抗体
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申请号: US12142594申请日: 2008-06-19
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公开(公告)号: US20090155250A1公开(公告)日: 2009-06-18
- 发明人: Zhaochun Chen , Patricia Earl , Bernard Moss , Suzanne U. Emerson , Robert H. Purcell
- 申请人: Zhaochun Chen , Patricia Earl , Bernard Moss , Suzanne U. Emerson , Robert H. Purcell
- 申请人地址: US MD Rockville
- 专利权人: The Gov. of the USA, as represented by The Secretary, Department of Health
- 当前专利权人: The Gov. of the USA, as represented by The Secretary, Department of Health
- 当前专利权人地址: US MD Rockville
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07K16/08 ; C12N15/39 ; C12N15/85 ; C12Q1/70 ; A61P31/20 ; C12N5/10 ; C12N5/16 ; C12N7/01
摘要:
The present invention relates to monoclonal antibodies that bind or neutralize Orthopoxviruses. The invention provides such antibodies, fragments of such antibodies retaining B5 or A33 binding ability, fully human antibodies retaining B5 or A33 binding ability, and pharmaceutical compositions including such antibodies. The invention further provides for isolated nucleic acids encoding the antibodies of the invention and host cells transformed therewith. Additionally, the invention provides for prophylactic, therapeutic, and diagnostic methods employing the antibodies and nucleic acids of the invention.
公开/授权文献
- US07914788B2 Monoclonal antibodies against orthopoxviruses 公开/授权日:2011-03-29
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