发明申请
- 专利标题: 2-ethyl N,N-bis(2-chloroethyl)phosphorodiamidates
- 专利标题(中): 2-乙基N,N-双(2-氯乙基)磷酰胺
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申请号: US11955177申请日: 2007-12-12
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公开(公告)号: US20090156559A1公开(公告)日: 2009-06-18
- 发明人: Edgardo Laborde , Andrew B. Kelson , Wenli Ma , Kevin T. Weber
- 申请人: Edgardo Laborde , Andrew B. Kelson , Wenli Ma , Kevin T. Weber
- 专利权人: Telik, Inc.
- 当前专利权人: Telik, Inc.
- 主分类号: A61K31/675
- IPC分类号: A61K31/675 ; C07F9/24 ; A61K31/664 ; A61P37/02 ; A61P35/00
摘要:
2-{[2-(Substituted amino)ethyl]sulfonyl}ethyl N,N-bis(2-chloroethyl)phosphorodiamidates and their salts, their preparation and intermediates in their preparation, pharmaceutical compositions containing them, and methods of treatment using them. The compounds are useful for treating cancer and autoimmune diseases, alone and in combination with other therapies.
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