发明申请
- 专利标题: DENDRITIC POLYMERS AND MAGNETIC RESONANCE IMAGING CONTRAST AGENT EMPLOYING THE SAME
- 专利标题(中): 透明聚合物和磁共振成像对比剂使用它
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申请号: US12174439申请日: 2008-07-16
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公开(公告)号: US20090169481A1公开(公告)日: 2009-07-02
- 发明人: Dhakshanamurthy Thirumalai , Chin-I Lin , Shian-Jy Wang
- 申请人: Dhakshanamurthy Thirumalai , Chin-I Lin , Shian-Jy Wang
- 申请人地址: TW Hsinchu
- 专利权人: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
- 当前专利权人: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
- 当前专利权人地址: TW Hsinchu
- 优先权: TW96151449 20071231
- 主分类号: A61K49/12
- IPC分类号: A61K49/12 ; C08G77/00
摘要:
A dendritic polymer and a magnetic resonance imaging contrast agent employing the same. The magnetic resonance contrast agent includes the dendritic polymer according to the structure of SP-DZ-L)i)j or SP-DX-Z-L)i)j, wherein, S is cyclosilane moiety with j silicon oxygen residual groups, and j is not less than 2; P is and 1 is not less than 1; D is a C3-30 dendritic moiety having n oxygen residue, and n is not less than 3; X is C3-30 moiety having bi-functional groups; Z is a C3-20 moiety having a plurality of functional group; and L is a metal cation.