发明申请
- 专利标题: Determination of sFlt-1:Angiogenic Factor Complex
- 专利标题(中): sFlt-1:血管生成因子复合物的测定
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申请号: US12350090申请日: 2009-01-07
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公开(公告)号: US20090176247A1公开(公告)日: 2009-07-09
- 发明人: George Bashirians , Deborah Byrne , Sarah Groulx , Sharon Jackson , Heather Lane-Brown , Banumathi Sankaran , Edward Scalice , Karen Yang , Jian Zheng
- 申请人: George Bashirians , Deborah Byrne , Sarah Groulx , Sharon Jackson , Heather Lane-Brown , Banumathi Sankaran , Edward Scalice , Karen Yang , Jian Zheng
- 主分类号: G01N33/53
- IPC分类号: G01N33/53 ; G01N33/566
摘要:
Methods for determining the presence or amount of a complex comprising a first and second molecular entity are provided, preferably an sFlt-1:PlGF complex. A determination of the presence or amount of the complex can be used in methods for predicting, detecting, monitoring a disease, or guiding therapy in respect to a disease such as vascular, vascular-related disease, cardiac, cardiac-related disease, cancer, cancer-related disease, preeclampsia, and preeclampsia-related disease. Determining sFlt-1:angiogenic factor complex is particularly useful for predicting and detecting preeclampsia in early stages of gestation and in stages of the disease where clinical evaluation may be uninformative.
公开/授权文献
- US08835183B2 Determination of sFlt-1:angiogenic factor complex 公开/授权日:2014-09-16