发明申请
US20090186343A1 METHODS FOR PREPARING MODIFIED BIOMOLECULES, MODIFIED BIOMOLECULES AND METHODS FOR USING SAME
审中-公开
制备改性生物分子的方法,改良生物分子及其使用方法
- 专利标题: METHODS FOR PREPARING MODIFIED BIOMOLECULES, MODIFIED BIOMOLECULES AND METHODS FOR USING SAME
- 专利标题(中): 制备改性生物分子的方法,改良生物分子及其使用方法
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申请号: US12035352申请日: 2008-02-21
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公开(公告)号: US20090186343A1公开(公告)日: 2009-07-23
- 发明人: Hongyi Wang , Norha Deluge , Kristi Kincaid , Yuri Belosludtsev , Tommie Lincecum, JR. , Amy Williams , Amy Bryant , Ming Fa , Benjamin Stevens , Susan H. Hardin
- 申请人: Hongyi Wang , Norha Deluge , Kristi Kincaid , Yuri Belosludtsev , Tommie Lincecum, JR. , Amy Williams , Amy Bryant , Ming Fa , Benjamin Stevens , Susan H. Hardin
- 申请人地址: US TX Houston
- 专利权人: VISIGEN BIOTECHNOLOGIES, INC.
- 当前专利权人: VISIGEN BIOTECHNOLOGIES, INC.
- 当前专利权人地址: US TX Houston
- 优先权: JPEP03002027.5 20030128
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C12P19/34
摘要:
A novel and efficient single pot synthetic schemes are disclosed for preparing modified nucleotides, nucleotide analogs, nucleotide polyphosphates, and nucleotide polyphosphate analogs. The novel method is used to prepare nucleotides, nucleotide analogs, nucleotide polyphosphates, and nucleotide polyphosphate analogs having non-persistent or persistent and non-persistent modifications. Novel biomolecular reactions are also disclosed using the novel modified biomolecules disclosed herein.
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