发明申请
US20090197894A1 NICOTINAMIDE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS
审中-公开
NICOTINAMIDE衍生物及其作为治疗药物使用
- 专利标题： NICOTINAMIDE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS
- 专利标题（中）： NICOTINAMIDE衍生物及其作为治疗药物使用
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申请号： US12423432申请日： 2009-04-14
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公开(公告)号： US20090197894A1公开(公告)日： 2009-08-06
- 发明人: Jian-Min Fu , Vishnumurthy Kodumuru , Shaoyi Sun , Michael D. Winther , Richard M. Fine , Daniel F. Harvey , Boris Klebansky , Mark P. Gray-Keller , Heinz W. Gschwend , Wenbao Li
- 申请人： Jian-Min Fu , Vishnumurthy Kodumuru , Shaoyi Sun , Michael D. Winther , Richard M. Fine , Daniel F. Harvey , Boris Klebansky , Mark P. Gray-Keller , Heinz W. Gschwend , Wenbao Li
- 申请人地址： CA Burnaby
- 专利权人： XENON PHARMACEUTICALS INC.
- 当前专利权人： XENON PHARMACEUTICALS INC.
- 当前专利权人地址： CA Burnaby
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; C07D401/04 ; A61P3/10
摘要：
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): where m, n, p, V, R1, R2, R3, R4, R5 and R6 are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
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