发明申请
US20090202563A1 C20ORF23 as modifier of the IGFR pathway and methods of use
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C20ORF23作为IGFR途径的修饰物和使用方法
- 专利标题: C20ORF23 as modifier of the IGFR pathway and methods of use
- 专利标题(中): C20ORF23作为IGFR途径的修饰物和使用方法
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申请号: US10592171申请日: 2005-03-10
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公开(公告)号: US20090202563A1公开(公告)日: 2009-08-13
- 发明人: Lori Friedman , Helen Francis-Lang , Annette L. Parks , Kenneth James Shaw , Lynn Margaret Bjerke , Timothy S. Heuer
- 申请人: Lori Friedman , Helen Francis-Lang , Annette L. Parks , Kenneth James Shaw , Lynn Margaret Bjerke , Timothy S. Heuer
- 申请人地址: US CA South San Francisco
- 专利权人: EXELIXIS, INC.
- 当前专利权人: EXELIXIS, INC.
- 当前专利权人地址: US CA South San Francisco
- 国际申请: PCT/US05/08127 WO 20050310
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; G01N33/68 ; G01N33/00 ; C12Q1/02 ; C12Q1/68 ; G01N33/566 ; A01K67/027 ; C12N5/06
摘要:
Human C20ORF23 genes are identified as modulators of the IGFR pathway, and thus are therapeutic targets for disorders associated with defective IGFR function. Methods for identifying modulators of IGFR, comprising screening for agents that modulate the activity of C20ORF23 are provided.
公开/授权文献
- US07943302B2 C20ORF23 as modifier of the IGFR pathway and methods of use 公开/授权日:2011-05-17
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