发明申请
US20090202618A1 Dna vaccines encoding hsp60 peptide fragments for treating autoimmune diseases
审中-公开
编码hsp60肽片段的Dna疫苗用于治疗自身免疫性疾病
- 专利标题： Dna vaccines encoding hsp60 peptide fragments for treating autoimmune diseases
- 专利标题（中）： 编码hsp60肽片段的Dna疫苗用于治疗自身免疫性疾病
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申请号： US10580176申请日： 2004-11-24
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公开(公告)号： US20090202618A1公开(公告)日： 2009-08-13
- 发明人: Irun R. Cohen , Francisco Quintana
- 申请人： Irun R. Cohen , Francisco Quintana
- 申请人地址： IL Revhovot
- 专利权人： Yeda Research & Development Co. Ltd
- 当前专利权人： Yeda Research & Development Co. Ltd
- 当前专利权人地址： IL Revhovot
- 国际申请： PCT/IL04/01080 WO 20041124
- 主分类号： A61K9/127
- IPC分类号： A61K9/127 ; C12N15/00 ; A61K39/00 ; A61K35/12 ; C12Q1/02
摘要：
The present invention is related to recombinant constructs encoding active fragments of HSP60 which are effective in treating T cell-mediated inflammatory autoimmune diseases by DNA vaccines. The HSP60 fragments of the present invention are identified by their ability to react with T cells isolated from an animal vaccinated with DNA constructs encoding HSP70 to induce Th2/3 T-cell responses.
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