发明申请
- 专利标题： Antibodies against flagellin and uses thereof
- 专利标题（中）： 抗鞭毛蛋白的抗体及其用途
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申请号： US12231797申请日： 2008-09-05
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公开(公告)号： US20090208506A1公开(公告)日： 2009-08-20
- 发明人: Nurit Rachamim , Andrew L. Salzman , Kanneganti Murthy
- 申请人： Nurit Rachamim , Andrew L. Salzman , Kanneganti Murthy
- 申请人地址： US MA Beverly IL Rehovot
- 专利权人： Inotek Pharmaceuticals Corporation,Yeda Research and Development Co., Ltd.
- 当前专利权人： Inotek Pharmaceuticals Corporation,Yeda Research and Development Co., Ltd.
- 当前专利权人地址： US MA Beverly IL Rehovot
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/00 ; C12N5/12 ; C12N15/13 ; C12N15/63
摘要：
The present invention provides a novel class of monoclonal antibodies which have a high affinity, broad spectrum neutralizing reactivity to flagellin from various Gram-negative bacteria including, but not limited to, E. coli, Salmonella, Serratia, Proteus, Enterobacter, Citrobacter, Campylobacter and Pseudomonas. The present invention further provides methods of treating inflammatory bowel disease (IBD) and methods of treating enterobacterial infections using anti-flagellin antibodies in humans, other animals and birds.
公开/授权文献
- US08263078B2 Antibodies against flagellin and uses thereof 公开/授权日：2012-09-11
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