发明申请
US20090215822A1 Substituted Oxadiazole Derivatives as Positive Allosteric Modulators of Metabotropic Glutamate Receptors
审中-公开
取代的恶二唑衍生物作为代谢型谷氨酸受体的正变构调节剂
- 专利标题： Substituted Oxadiazole Derivatives as Positive Allosteric Modulators of Metabotropic Glutamate Receptors
- 专利标题（中）： 取代的恶二唑衍生物作为代谢型谷氨酸受体的正变构调节剂
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申请号： US11920603申请日： 2006-05-17
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公开(公告)号： US20090215822A1公开(公告)日： 2009-08-27
- 发明人: Marco Farina , Stefania Gagliardi , Emmanuel Le Poul , Vincent Mutel , Giovanni Palombi , Sonia-Maria Poli , Jean-Philippe Rocher
- 申请人： Marco Farina , Stefania Gagliardi , Emmanuel Le Poul , Vincent Mutel , Giovanni Palombi , Sonia-Maria Poli , Jean-Philippe Rocher
- 申请人地址： IT Milan CH Geneva
- 专利权人： NIKEM RESEARCH SRL,ADDEX PHARMA SA
- 当前专利权人： NIKEM RESEARCH SRL,ADDEX PHARMA SA
- 当前专利权人地址： IT Milan CH Geneva
- 优先权： GB0510138.1 20050518; GB0601709.9 20060127
- 国际申请： PCT/IB2006/001881 WO 20060517
- 主分类号： A61K31/4545
- IPC分类号： A61K31/4545 ; C07D413/04 ; A61K31/454 ; C07D413/14 ; A61P25/18
摘要：
The present invention relates to new compounds which are Oxadiazole derivatives of formula (I) wherein B, P, Q, W, R1 and R2 are defined in the description. Invention compounds are useful in the prevention or treatment of central or peripheral nervous system disorders as well as other disorders modulated by mGluR5 receptors.(I).
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