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公开(公告)号：US08772314B2
公开(公告)日：2014-07-08
申请号：US13303413
申请日：2011-11-23
申请人： Gabriele Amari , Mauro Riccaboni , Marco Farina
发明人： Gabriele Amari , Mauro Riccaboni , Marco Farina
IPC分类号： A61K31/44 , C07D453/02
CPC分类号： C07D207/12 , C07D451/10 , C07D453/02
摘要： Alkaloid aminoester derivatives according to formula (I) and (VI) act as muscarinic receptor antagonists.
摘要翻译： 式（I）和（VI）的生物碱类氨基酯衍生物作为毒蕈碱受体拮抗剂。
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2.发明申请公开(公告)号：US20100097491A1
公开(公告)日：2010-04-22
申请号：US12288626
申请日：2008-10-21
IPC分类号： H04N9/73
CPC分类号： H04N5/23238 , H04N9/045 , H04N9/09
摘要： In one embodiment, a light sensor includes four cell arrays, one for each color of the Bayer pattern, and four lenses each focusing the light coming from the scene to be captured on a respective cell array. The lenses are oriented such that at least a second green image, commonly provided by the fourth cell array, is both horizontally and vertically shifted (spaced) apart by half a pixel pitch from a first (reference) green image. In a second embodiment, the four lenses are oriented such that the red and blue images are respectively shifted (spaced) apart by half a pixel pitch from the first or reference green image, one horizontally and the other vertically, and the second green image is shifted (spaced) apart by half a pixel pitch from the reference green image both horizontally and vertically.
摘要翻译： 在一个实施例中，光传感器包括四个单元阵列，一个用于拜耳图案的每种颜色，四个透镜将来自场景的光聚焦在相应的单元阵列上。 透镜被取向为使得通常由第四单元阵列提供的至少第二绿色图像与第一（参考）绿色图像水平和垂直地移位（间隔开）半个像素间距。 在第二实施例中，四个透镜被定向成使得红色和蓝色图像分别从第一或参考绿色图像分开移位（间隔开）半个像素间距，一个水平方向和另一个垂直方向偏移，并且第二绿色图像是 在参考绿色图像水平和垂直方向上移动（间隔开）半个像素间距。
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3.发明申请Substituted Oxadiazole Derivatives as Positive Allosteric Modulators of Metabotropic Glutamate Receptors 审中-公开取代的恶二唑衍生物作为代谢型谷氨酸受体的正变构调节剂公开(公告)号：US20090215822A1
公开(公告)日：2009-08-27
申请号：US11920603
申请日：2006-05-17
申请人： Marco Farina , Stefania Gagliardi , Emmanuel Le Poul , Vincent Mutel , Giovanni Palombi , Sonia-Maria Poli , Jean-Philippe Rocher
发明人： Marco Farina , Stefania Gagliardi , Emmanuel Le Poul , Vincent Mutel , Giovanni Palombi , Sonia-Maria Poli , Jean-Philippe Rocher
IPC分类号： A61K31/4545 , C07D413/04 , A61K31/454 , C07D413/14 , A61P25/18
CPC分类号： C07D413/04 , C07D413/14 , C07D417/14
摘要： The present invention relates to new compounds which are Oxadiazole derivatives of formula (I) wherein B, P, Q, W, R1 and R2 are defined in the description. Invention compounds are useful in the prevention or treatment of central or peripheral nervous system disorders as well as other disorders modulated by mGluR5 receptors.(I).
摘要翻译： 本发明涉及新的化合物，其是式（I）的恶二唑衍生物，其中B，P，Q，W，R 1和R 2在说明书中定义。 本发明化合物可用于预防或治疗中枢或周围神经系统疾病以及由mGluR5受体调节的其它障碍。（I）。
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4.发明授权Soft-computing method for establishing the heat dissipation law in a diesel common rail engine 有权在柴油共轨发动机中建立散热定律的软计算方法公开(公告)号：US07369935B2
公开(公告)日：2008-05-06
申请号：US11527012
申请日：2006-09-25
申请人： Nicola Cesario , Claudio Muscio , Marco Farina , Paolo Amato
发明人： Nicola Cesario , Claudio Muscio , Marco Farina , Paolo Amato
CPC分类号： F02D41/3809 , F02D35/023 , F02D41/1405 , F02D2200/0625
摘要： A soft-computing method for establishing the dissipation law of the heat in a diesel Common Rail engine, in particular for establishing the dissipation mean speed (HRR) of the heat, includes the following steps: choosing a number of Wiebe functions whereon a dissipation speed signal (HRR) of the heat is decomposed; applying a Transform Ψ to the dissipation speed signal (HRR) of the heat; carrying out analysis of homogeneity of the Transform Ψ output; realizing a corresponding neural network MLP wherein the design is guided by an evolutive algorithm; and training and testing the neural network MLP.
摘要翻译： 一种用于建立柴油共轨发动机中的热量耗散定律的软计算方法，特别是用于确定散热平均速度（HRR）的方法，包括以下步骤：选择一些威布函数，其中耗散速度 信号（HRR）的热分解; 将变形Psi应用于散热速度信号（HRR）; 对变形Psi输出的均匀性进行分析; 实现相应的神经网络MLP，其中设计由演进算法引导; 并训练和测试神经网络MLP。
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公开(公告)号：US08436909B2
公开(公告)日：2013-05-07
申请号：US12288626
申请日：2008-10-21
IPC分类号： H04N5/228
CPC分类号： H04N5/23238 , H04N9/045 , H04N9/09
摘要： In one embodiment, a light sensor includes four cell arrays, one for each color of the Bayer pattern, and four lenses each focusing the light coming from the scene to be captured on a respective cell array. The lenses are oriented such that at least a second green image, commonly provided by the fourth cell array, is both horizontally and vertically shifted (spaced) apart by half a pixel pitch from a first (reference) green image. In a second embodiment, the four lenses are oriented such that the red and blue images are respectively shifted (spaced) apart by half a pixel pitch from the first or reference green image, one horizontally and the other vertically, and the second green image is shifted (spaced) apart by half a pixel pitch from the reference green image both horizontally and vertically.
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公开(公告)号：US20120134934A1
公开(公告)日：2012-05-31
申请号：US13303413
申请日：2011-11-23
申请人： Gabriele AMARI , Mauro Riccaboni , Marco Farina
发明人： Gabriele AMARI , Mauro Riccaboni , Marco Farina
IPC分类号： A61K31/439 , C07D451/06 , A61K31/46 , C07D207/12 , A61K31/40 , C07D409/06 , A61K31/4025 , A61P11/08 , A61P29/00 , A61P11/06 , A61P11/00 , A61K9/12 , A61M15/00 , A61M11/04 , A61M11/02 , C07D453/02
CPC分类号： C07D207/12 , C07D451/10 , C07D453/02
摘要： Alkaloid aminoester derivatives according to formula (I) and (VI) act as muscarinic receptor antagonists.
摘要翻译： 式（I）和（VI）的生物碱类氨基酯衍生物作为毒蕈碱受体拮抗剂。
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7.发明申请Soft-computing method for establishing the heat dissipation law in a diesel common rail engine 有权在柴油共轨发动机中建立散热定律的软计算方法公开(公告)号：US20070021902A1
公开(公告)日：2007-01-25
申请号：US11527012
申请日：2006-09-25
申请人： Nicola Cesario , Claudio Muscio , Marco Farina , Paolo Amato
发明人： Nicola Cesario , Claudio Muscio , Marco Farina , Paolo Amato
CPC分类号： F02D41/3809 , F02D35/023 , F02D41/1405 , F02D2200/0625
摘要： A soft-computing method for establishing the dissipation law of the heat in a diesel Common Rail engine, in particular for establishing the dissipation mean speed (HRR) of the heat, includes the following steps: choosing a number of Wiebe functions whereon a dissipation speed signal (HRR) of the heat is decomposed; applying a Transform Ψ to the dissipation speed signal (HRR) of the heat; carrying out analysis of homogeneity of the Transform Ψ output; realizing a corresponding neural network MLP wherein the design is guided by an evolutive algorithm; and training and testing the neural network MLP.
摘要翻译： 一种用于建立柴油共轨发动机中的热量耗散定律的软计算方法，特别是用于确定散热平均速度（HRR）的方法，包括以下步骤：选择一些威布函数，其中耗散速度 信号（HRR）的热分解; 将变形Psi应用于散热速度信号（HRR）; 对变形Psi输出的均匀性进行分析; 实现相应的神经网络MLP，其中设计由演进算法引导; 并训练和测试神经网络MLP。
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8.发明授权Soft-computing method for establishing the heat dissipation law in a diesel common rail engine 有权在柴油共轨发动机中建立散热定律的软计算方法公开(公告)号：US07120533B2
公开(公告)日：2006-10-10
申请号：US11142914
申请日：2005-05-31
申请人： Nicola Cesario , Claudio Muscio , Marco Farina , Paolo Amato
发明人： Nicola Cesario , Claudio Muscio , Marco Farina , Paolo Amato
CPC分类号： F02D41/3809 , F02D35/023 , F02D41/1405 , F02D2200/0625
摘要： A soft-computing method for establishing the dissipation law of the heat in a diesel Common Rail engine, in particular for establishing the dissipation mean speed (HRR) of the heat, includes the following steps: choosing a number of Wiebe functions whereon a dissipation speed signal (HRR) of the heat is decomposed; applying a Transform Ψ to the dissipation speed signal (HRR) of the heat; carrying out analysis of homogeneity of the Transform Ψ output; realizing a corresponding neural network MLP wherein the design is guided by an evolutive algorithm; and training and testing the neural network MLP.
摘要翻译： 一种用于建立柴油共轨发动机中的热量耗散定律的软计算方法，特别是用于确定散热平均速度（HRR）的方法，包括以下步骤：选择一些威布函数，其中耗散速度 信号（HRR）的热分解; 将变形Psi应用于散热速度信号（HRR）; 对变形Psi输出的均匀性进行分析; 实现相应的神经网络MLP，其中设计由演进算法引导; 并训练和测试神经网络MLP。
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9.发明申请Novel Heterocyclic Compounds as Positive Allosteric Modulators of Metabotropic Glutamate Receptors 审中-公开新型杂环化合物作为代谢型谷氨酸受体的正变构调节剂公开(公告)号：US20100004284A1
公开(公告)日：2010-01-07
申请号：US11920597
申请日：2006-05-17
IPC分类号： A61K31/4545 , C07D401/04 , C07D211/84 , A61K31/454 , A61P25/18
CPC分类号： C07D401/04 , C07D413/04 , C07D413/14
摘要： The present invention relates to new compounds which are Heterocyclic derivatives of formula (I) wherein A, B, P, X, Y, Q, W, R1 and R2 are defined in the description. Invention compounds are useful for treating central or peripheral nervous system disorders and other disorders which are affected by the neuromodulatory effect of mGluR5 positive allosteric modulators such as cognitive decline and also to treat both positive and negative symptoms in schizophrenia.
摘要翻译： 本发明涉及作为其中A，B，P，X，Y，Q，W，R 1和R 2在本说明书中定义的式（I）的杂环衍生物的新化合物。 本发明化合物可用于治疗受到mGluR5阳性变构调节剂如认知衰退的神经调节作用影响的中枢性或周围神经系统疾病和其它疾病，并且还可用于治疗精神分裂症中的阳性和阴性症状。
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10.发明申请Soft-computing method for establishing the heat dissipation law in a diesel common rail engine 有权在柴油共轨发动机中建立散热定律的软计算方法公开(公告)号：US20050273244A1
公开(公告)日：2005-12-08
申请号：US11142914
申请日：2005-05-31
申请人： Nicola Cesario , Claudio Muscio , Marco Farina , Paolo Amato
发明人： Nicola Cesario , Claudio Muscio , Marco Farina , Paolo Amato
CPC分类号： F02D41/3809 , F02D35/023 , F02D41/1405 , F02D2200/0625
摘要： A soft-computing method for establishing the dissipation law of the heat in a diesel Common Rail engine, in particular for establishing the dissipation mean speed (HRR) of the heat, includes the following steps: choosing a number of Wiebe functions whereon a dissipation speed signal (HRR) of the heat is decomposed; applying a Transform Ψ to the dissipation speed signal (HRR) of the heat; carrying out analysis of homogeneity of the Transform Ψ output; realizing a corresponding neural network MLP wherein the design is guided by an evolutive algorithm; and training and testing the neural network MLP.
摘要翻译： 一种用于建立柴油共轨发动机中的热量耗散定律的软计算方法，特别是用于确定散热平均速度（HRR）的方法，包括以下步骤：选择一些威布函数，其中耗散速度 信号（HRR）的热分解; 将变形Psi应用于散热速度信号（HRR）; 对变形Psi输出的均匀性进行分析; 实现相应的神经网络MLP，其中设计由演进算法引导; 并训练和测试神经网络MLP。
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