发明申请
US20090220517A1 METHOD FOR PRODUCING EPITOMERS AND THEIR USES ON CARRIER MICROORGANISMS
审中-公开
生产护肤品的方法及其在载体微生物中的应用
- 专利标题： METHOD FOR PRODUCING EPITOMERS AND THEIR USES ON CARRIER MICROORGANISMS
- 专利标题（中）： 生产护肤品的方法及其在载体微生物中的应用
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申请号： US12162804申请日： 2006-11-29
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公开(公告)号： US20090220517A1公开(公告)日： 2009-09-03
- 发明人: Veit Braun , Christoph Von Eichel-Streiber , Ralf Jochem
- 申请人： Veit Braun , Christoph Von Eichel-Streiber , Ralf Jochem
- 申请人地址： DE Mainz
- 专利权人： tgcBIOMICS GmbH
- 当前专利权人： tgcBIOMICS GmbH
- 当前专利权人地址： DE Mainz
- 优先权： DE102006004612.9 20060201
- 国际申请： PCT/EP06/11461 WO 20061129
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61K39/00 ; A61K39/02 ; A61K35/74 ; A61K35/66 ; A61K35/12 ; C12N15/09
摘要：
The present invention relates to a method for producing carrier microorganisms, in particular bacteria, which, through targeted genetic manipulation, carry epitopes or epitomers, respectively, on their surfaces. Epitomers are antigenically effective epitopes that can be found in the polypeptide chain in multiple identical copies, and which, when expressed on the surface of the bacteria, can be used for immunization with particular success. A further aspect relates to correspondingly produced bacteria and their uses as vaccines, in particular in cancer therapy.
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