- 专利标题: Nuclear reprogramming factor and induced pluripotent stem cells
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申请号: US12289873申请日: 2008-11-06
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公开(公告)号: US20090227032A1公开(公告)日: 2009-09-10
- 发明人: Shinya Yamanaka , Kazutoshi Takahashi , Masato Nakagawa
- 申请人: Shinya Yamanaka , Kazutoshi Takahashi , Masato Nakagawa
- 申请人地址: JP Kyoto
- 专利权人: Kyoto University
- 当前专利权人: Kyoto University
- 当前专利权人地址: JP Kyoto
- 优先权: JP2005-359537 20051213
- 主分类号: C12N15/86
- IPC分类号: C12N15/86 ; C12N5/00 ; C12N5/08 ; C12N5/06 ; C12N5/10
摘要:
The present invention relates to a nuclear reprogramming factor having an action of reprogramming a differentiated somatic cell to derive an induced pluripotent stem (iPS) cell. The present invention also relates to the aforementioned iPS cells, methods of generating and maintaining iPS cells, and methods of using iPS cells, including screening and testing methods as well as methods of stem cell therapy. The present invention also relates to somatic cells derived by inducing differentiation of the aforementioned iPS cells.
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