发明申请
- 专利标题： AROMATIC ETHER DERIVATIVES USEFUL AS THROMBIN INHIBITORS
- 专利标题（中）： 芳香醚衍生物有效用作血栓抑制剂
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申请号： US11719415申请日： 2005-11-10
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公开(公告)号： US20090227566A1公开(公告)日： 2009-09-10
- 发明人: Ankush Baburao Argade , Theodore Goodson, JR. , David Kent Herron , Sajan Joseph , Salvatore Donato Lepore , Angela Lynn Marquart , John Joseph Masters , David Mendel , Leander Merritt , Andrew Michael Ratz , Gerald Floyd Smith , Anne Lousie Tebbe , Michael Robert Wiley , Ying Kwong Yee
- 申请人： Ankush Baburao Argade , Theodore Goodson, JR. , David Kent Herron , Sajan Joseph , Salvatore Donato Lepore , Angela Lynn Marquart , John Joseph Masters , David Mendel , Leander Merritt , Andrew Michael Ratz , Gerald Floyd Smith , Anne Lousie Tebbe , Michael Robert Wiley , Ying Kwong Yee
- 国际申请： PCT/US2005/041161 WO 20051110
- 主分类号： A61K31/551
- IPC分类号： A61K31/551 ; A61K31/5377 ; A61K31/445 ; C07D243/08 ; C07D413/12 ; C07D401/12 ; C07D211/98
摘要：
This application relates to a compound of formula (I) (or a pharmaceutically acceptable salt of the compound or prodrug thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa and/or thrombin, as well as a process for its preparation and intermediates therefor. An example of a compound of formula (I) is (a).
公开/授权文献
- US07700628B2 Aromatic ether derivatives useful as thrombin inhibitors 公开/授权日：2010-04-20
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