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发明申请
US20090233876A1 Water Soluble and Activable Phenolics Derivatives with Dermocosmetic and Therapeutic Applications and Process for Preparing Said Derivatives 审中-公开
具有皮肤科学和治疗应用的水溶性和活性酚类衍生物以及用于制备所述衍生物的方法

Water Soluble and Activable Phenolics Derivatives with Dermocosmetic and Therapeutic Applications and Process for Preparing Said Derivatives
摘要：
The invention relates to the preparation of phenolics derivatives by enzymatic condensation of phenolics selected among pyrocatechol or its derivatives with the glucose moiety of sucrose. The production of said phenolics derivatives is achieved with a glucosyltransferase (EC 2.4.1.5). These O-α-glucosides of selected phenolics are new, have a solubility in water higher than that of their parent polyphenol and have useful applications in cosmetic and pharmaceutical compositions, such as antioxidative, antiviral, antibacterial, immune-stimulating, antiallergic, antihypertensive, antiischemic, antiarrhythmic, antithrombotic, hypocholesterolemic, antilipoperoxidant, hepatoprotective, anti-inflammatory, anticarcinogenic antimutagenic, antineoplastic, anti-thrombotic, and vasodilatory formulations, or in any other field of application.
摘要（中）：

本发明涉及通过将选自邻苯二酚或其衍生物的酚类与蔗糖的葡萄糖部分的酶缩合制备酚衍生物。 所述酚衍生物的生产通过葡糖基转移酶（EC 2.4.1.5）来实现。 所选择的酚类的这些O-α-葡萄糖苷是新的，在水中的溶解度高于其亲本多酚的溶解度，并且在化妆品和药物组合物中有用，例如抗氧化，抗病毒，抗菌，免疫刺激，抗过敏，抗高血压， 抗缺血性，抗心律不齐，抗血栓形成，低胆固醇血症，抗脂质过氧化物，肝保护，抗炎，抗致癌性抗诱发剂，抗肿瘤剂，抗血栓形成和血管扩张制剂，或在任何其他应用领域。

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