发明申请
US20090253634A1 Methods and Compositions for the Treatment of Gastrointestinal Disorders
审中-公开
用于治疗胃肠道疾病的方法和组合
- 专利标题: Methods and Compositions for the Treatment of Gastrointestinal Disorders
- 专利标题(中): 用于治疗胃肠道疾病的方法和组合
-
申请号: US12064116申请日: 2006-08-21
-
公开(公告)号: US20090253634A1公开(公告)日: 2009-10-08
- 发明人: Mark G. Currie , Shalina Mahajan-Miklos , Angelika Fretzen , Li Jing Sun , Caroline Kurtz , G. Todd Milne , Thea Norman , Shannon Roberts , E. Kelly Sullivan
- 申请人: Mark G. Currie , Shalina Mahajan-Miklos , Angelika Fretzen , Li Jing Sun , Caroline Kurtz , G. Todd Milne , Thea Norman , Shannon Roberts , E. Kelly Sullivan
- 申请人地址: US MA Cambridge
- 专利权人: MICROBIA, INC.
- 当前专利权人: MICROBIA, INC.
- 当前专利权人地址: US MA Cambridge
- 国际申请: PCT/US06/32719 WO 20060821
- 主分类号: A61K38/10
- IPC分类号: A61K38/10 ; C07K7/00
摘要:
The present invention features compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastnoesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, Inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), and disorders and conditions associated with constipation, e.g. constipation associated with use of opiate pain killers, post-surgical constipation (post-operative ileus), and constipation associated with neuropathic disorders as well as other conditions and disorders using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.