发明申请
US20090258391A1 RECOMBINANT CELL CLONES HAVING INCREASED STABILITY AND METHODS OF MAKING AND USING SAME
审中-公开
具有增加的稳定性的重组细胞克隆及其制备和使用方法
- 专利标题： RECOMBINANT CELL CLONES HAVING INCREASED STABILITY AND METHODS OF MAKING AND USING SAME
- 专利标题（中）： 具有增加的稳定性的重组细胞克隆及其制备和使用方法
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申请号： US12488441申请日： 2009-06-19
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公开(公告)号： US20090258391A1公开(公告)日： 2009-10-15
- 发明人: Manfred Reiter , Wolfgang Mundt , Friedrich Dorner
- 申请人： Manfred Reiter , Wolfgang Mundt , Friedrich Dorner
- 申请人地址： AT Vienna
- 专利权人： Baxter Aktiengesellschaft
- 当前专利权人： Baxter Aktiengesellschaft
- 当前专利权人地址： AT Vienna
- 优先权： AT1073/97 19970620
- 主分类号： C12P21/00
- IPC分类号： C12P21/00 ; C12Q1/02 ; C12N5/06
摘要：
Disclosed are a stable recombinant cell clones which are stable in serum- and protein-free medium for at least 40 generations, a biomass obtained by multiplying the stable cell clone under serum- and protein-free culturing conditions, and a method of preparing recombinant proteins by means of the biomass. Furthermore, the invention relates to a method of recovering stable recombinant cell clones.
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