发明申请
- 专利标题: Compound With Antimalarial Activity And Antimalarial Drug Containing The Same As Active Ingredient
- 专利标题(中): 具有抗疟活性的化合物和含有作为活性成分的抗疟药
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申请号: US12224387申请日: 2007-02-26
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公开(公告)号: US20090275612A1公开(公告)日: 2009-11-05
- 发明人: Tsunehiko Higuchi , Hirohisa Omiya , Naoki Umezawa , Hye-Sook Kim , Yusuke Wataya
- 申请人: Tsunehiko Higuchi , Hirohisa Omiya , Naoki Umezawa , Hye-Sook Kim , Yusuke Wataya
- 申请人地址: JP Nagoya-shi
- 专利权人: Nagoya City University
- 当前专利权人: Nagoya City University
- 当前专利权人地址: JP Nagoya-shi
- 优先权: JP2006-049678 20060227
- 国际申请: PCT/JP2007/053537 WO 20070226
- 主分类号: A61K31/4709
- IPC分类号: A61K31/4709 ; C07D215/38 ; A61P33/06
摘要:
Compounds with high antimalarial activity; and antimalarial drugs containing the same as an active ingredient. There are provided compounds with antimalarial activity represented by the chemical formula: (wherein R1 is H, Cl or OCH3; R2 is H or CH3; R3 is CH, CH2, C(CH3), CH(CH3) or C(CH3)2; Ar is imidazole, triazole, pyridine, benzene, pyrrole, furan, thiophene or derivatives thereof; n is 1 to 5; and m is 1 to 5). Further, there are provided antimalarial drugs containing these compounds with antimalarial activity or pharmacologically acceptable salts thereof as active ingredients.
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