发明申请
US20090298820A1 3-SUBSTITUTED-1H-PYRROLO[2,3-B]PYRIDINE AND 3-SUBSTITUTED-1H-PYRROLO[3,2-B]PYRIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES
审中-公开
3-取代的1H-吡咯并[2,3-b]吡啶和3-取代的1H-吡咯[3,2-B]吡啶化合物，它们作为MTOR激酶和PI3激酶抑制剂使用，以及它们的合成
![3-SUBSTITUTED-1H-PYRROLO[2,3-B]PYRIDINE AND 3-SUBSTITUTED-1H-PYRROLO[3,2-B]PYRIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES](/docs/US/2009-12-03/US20090298820A1/abs.jpg.600x600.jpg)
- 专利标题： 3-SUBSTITUTED-1H-PYRROLO[2,3-B]PYRIDINE AND 3-SUBSTITUTED-1H-PYRROLO[3,2-B]PYRIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES
- 专利标题（中）： 3-取代的1H-吡咯并[2,3-b]吡啶和3-取代的1H-吡咯[3,2-B]吡啶化合物，它们作为MTOR激酶和PI3激酶抑制剂使用，以及它们的合成
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申请号： US12473658申请日： 2009-05-28
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公开(公告)号： US20090298820A1公开(公告)日： 2009-12-03
- 发明人: Hwei-Ru Tsou , Gary Harold Birnberg , Gloria Jean MacEwan , Semiramis Ayral-Kaloustian , Matthew Gregory Bursavich , Sabrina Lombardi , Nan Zhang , Adam Matthew Gilbert , George Theordore Grosu , Natasja Brooijmans , Thai Hiep Nguyen
- 申请人： Hwei-Ru Tsou , Gary Harold Birnberg , Gloria Jean MacEwan , Semiramis Ayral-Kaloustian , Matthew Gregory Bursavich , Sabrina Lombardi , Nan Zhang , Adam Matthew Gilbert , George Theordore Grosu , Natasja Brooijmans , Thai Hiep Nguyen
- 申请人地址： US NJ Madison
- 专利权人： Wyeth
- 当前专利权人： Wyeth
- 当前专利权人地址： US NJ Madison
- 主分类号： A61K31/437
- IPC分类号： A61K31/437 ; A61K31/5375 ; A61K31/5377 ; A61K31/496 ; C07D471/04 ; A61P35/00 ; C07D498/08 ; A61P29/00 ; A61P17/00 ; A61P19/00
![3-SUBSTITUTED-1H-PYRROLO[2,3-B]PYRIDINE AND 3-SUBSTITUTED-1H-PYRROLO[3,2-B]PYRIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES](/abs-image/US/2009/12/03/US20090298820A1/abs.jpg.150x150.jpg)
摘要：
The invention relates to 3-substituted-1H-pyrrolo[2,3-b]pyridine, and 3-substituted-1H-pyrrolo[3,2-b]pyridine compounds of the Formula 1: or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein, compositions comprising the compounds, and methods for making and using the compounds.
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