发明申请
US20090306079A1 3,4-DI-SUBSTITUTED CYCLOBUTENE-1,2-DIONES AS CXC-CHEMOKINE RECEPTOR LIGANDS
有权
作为CXC-CHEMOKINE受体配体的3,4-二取代的环己基-1,2-二酮
- 专利标题： 3,4-DI-SUBSTITUTED CYCLOBUTENE-1,2-DIONES AS CXC-CHEMOKINE RECEPTOR LIGANDS
- 专利标题（中）： 作为CXC-CHEMOKINE受体配体的3,4-二取代的环己基-1,2-二酮
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申请号： US12352781申请日： 2009-01-13
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公开(公告)号： US20090306079A1公开(公告)日： 2009-12-10
- 发明人: Arthur G. Taveras , Cynthia J. Aki , Richard W. Bond , Jianping Chao , Michael Dwyer , Johan A. Ferreira , Jianhua Chao , Younong Yu , John J. Baldwin , Bernd Kaiser , Ge Li , J. Robert Merritt , Purakkattle J. Biju , Kingsley H. Nelson, JR. , Laura L. Rokosz , Gaifa Lai , James P. Jakway , Minglang Wu , Evan A. Hecker , Daniel Lundell , Jay S. Fine
- 申请人： Arthur G. Taveras , Cynthia J. Aki , Richard W. Bond , Jianping Chao , Michael Dwyer , Johan A. Ferreira , Jianhua Chao , Younong Yu , John J. Baldwin , Bernd Kaiser , Ge Li , J. Robert Merritt , Purakkattle J. Biju , Kingsley H. Nelson, JR. , Laura L. Rokosz , Gaifa Lai , James P. Jakway , Minglang Wu , Evan A. Hecker , Daniel Lundell , Jay S. Fine
- 专利权人： Schering Corporation,Pharmacopeia, Inc.
- 当前专利权人： Schering Corporation,Pharmacopeia, Inc.
- 主分类号： A61K31/535
- IPC分类号： A61K31/535 ; C07D401/04 ; C07D295/14 ; A61P37/02 ; A61P9/12 ; A61K31/497
摘要：
There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.
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