发明申请
- 专利标题: PROCESS FOR PRODUCTION OF 4-OXOQUINOLINE COMPOUND
- 专利标题(中): 4-氧杂环戊烯化合物的生产方法
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申请号: US12281921申请日: 2007-03-06
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公开(公告)号: US20090318702A1公开(公告)日: 2009-12-24
- 发明人: Koji Matsuda , Koji Ando , Shigeji Ohki , Takahiro Yamasaki , Jun-ichi Hoshi
- 申请人: Koji Matsuda , Koji Ando , Shigeji Ohki , Takahiro Yamasaki , Jun-ichi Hoshi
- 优先权: JP2006-060274 20060306; JP2006-060297 20060306
- 国际申请: PCT/JP2007/054311 WO 20070306
- 主分类号: C07D215/233
- IPC分类号: C07D215/233 ; C07C229/34 ; C07C69/612 ; C07C49/303
摘要:
The present invention provides a compound useful as a synthetic intermediate for an anti-HIV agent having an integrase inhibitory activity, a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate. Specifically, the present invention provides, for example, compounds represented by the formulas (6), (7-1), (7-2) and (8): wherein R is a fluorine atom or a methoxy group, R1 is a C1-C4 alkyl group, R2 is a hydroxyl-protecting group, and X2 is a halogen atom, a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate.
公开/授权文献
- US08420821B2 Process for production of 4-oxoquinoline compound 公开/授权日:2013-04-16
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