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公开(公告)号:US08383819B2
公开(公告)日:2013-02-26
申请号:US12281889
申请日:2007-03-06
申请人: Koji Matsuda , Koji Ando , Shigeji Ohki , Jun-ichi Hoshi , Takahiro Yamasaki
发明人: Koji Matsuda , Koji Ando , Shigeji Ohki , Jun-ichi Hoshi , Takahiro Yamasaki
IPC分类号: C07D215/00
CPC分类号: C07C229/30 , C07C43/215 , C07C57/72 , C07C57/76 , C07C61/40 , C07C67/333 , C07C67/343 , C07C69/708 , C07C69/716 , C07C69/738 , C07C69/92 , C07C69/94 , C07C229/34 , C07D215/56
摘要: The present invention provides a compound useful as a synthetic intermediate for an anti-HIV agent having an integrase inhibitory activity, and a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate. Specifically, for example, a compound represented by the formula (2′): wherein R is a fluorine atom or a methoxy group, and R400 is a hydrogen atom or a C1-C4 alkyl group, or a salt thereof, and a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate.
摘要翻译: 本发明提供了可用作具有整合酶抑制活性的抗HIV剂的合成中间体的化合物及其制备方法,以及使用该合成中间体的抗HIV剂的制备方法。 具体而言,例如,式(2')表示的化合物或其盐,其中R为氟原子或甲氧基,R400为氢原子或C1-C4烷基, 以及使用该合成中间体的抗HIV剂的制造方法。
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公开(公告)号:US20090318702A1
公开(公告)日:2009-12-24
申请号:US12281921
申请日:2007-03-06
申请人: Koji Matsuda , Koji Ando , Shigeji Ohki , Takahiro Yamasaki , Jun-ichi Hoshi
发明人: Koji Matsuda , Koji Ando , Shigeji Ohki , Takahiro Yamasaki , Jun-ichi Hoshi
IPC分类号: C07D215/233 , C07C229/34 , C07C69/612 , C07C49/303
CPC分类号: C07C229/30 , C07C65/21 , C07C69/716 , C07C229/34 , C07D215/233 , C07D215/56 , C07F7/1804 , Y02P20/55
摘要: The present invention provides a compound useful as a synthetic intermediate for an anti-HIV agent having an integrase inhibitory activity, a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate. Specifically, the present invention provides, for example, compounds represented by the formulas (6), (7-1), (7-2) and (8): wherein R is a fluorine atom or a methoxy group, R1 is a C1-C4 alkyl group, R2 is a hydroxyl-protecting group, and X2 is a halogen atom, a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate.
摘要翻译: 本发明提供了可用作具有整合酶抑制活性的抗HIV剂的合成中间体的化合物,其制备方法和使用该合成中间体的抗HIV药物的制备方法。 具体地说,本发明提供例如由式(6),(7-1),(7-2)和(8)表示的化合物:其中R是氟原子或甲氧基,R1是C1 -C4烷基,R2为羟基保护基,X2为卤素原子,其制造方法以及使用该合成中间体的抗HIV剂的制造方法。
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公开(公告)号:US08420821B2
公开(公告)日:2013-04-16
申请号:US12281921
申请日:2007-03-06
申请人: Koji Matsuda , Koji Ando , Shigeji Ohki , Takahiro Yamasaki , Jun-ichi Hoshi
发明人: Koji Matsuda , Koji Ando , Shigeji Ohki , Takahiro Yamasaki , Jun-ichi Hoshi
IPC分类号: C07D215/233
CPC分类号: C07C229/30 , C07C65/21 , C07C69/716 , C07C229/34 , C07D215/233 , C07D215/56 , C07F7/1804 , Y02P20/55
摘要: The present invention provides a compound useful as a synthetic intermediate for an anti-HIV agent having an integrase inhibitory activity, a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate. Specifically, the present invention provides, for example, compounds represented by the formulas (6), (7-1), (7-2) and (8): wherein R is a fluorine atom or a methoxy group, R1 is a C1-C4 alkyl group, R2 is a hydroxyl-protecting group, and X2 is a halogen atom, a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate.
摘要翻译: 本发明提供了可用作具有整合酶抑制活性的抗HIV剂的合成中间体的化合物,其制备方法和使用该合成中间体的抗HIV药物的制备方法。 具体地说,本发明提供例如由式(6),(7-1),(7-2)和(8)表示的化合物:其中R是氟原子或甲氧基,R1是C1 -C4烷基,R2为羟基保护基,X2为卤素原子,其制造方法以及使用该合成中间体的抗HIV剂的制造方法。
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公开(公告)号:US20090036684A1
公开(公告)日:2009-02-05
申请号:US12281889
申请日:2007-03-06
申请人: Koji Matsuda , Koji Ando , Shigeki Ohki , Jun-ichi Hoshi , Takahiro Yamasaki
发明人: Koji Matsuda , Koji Ando , Shigeki Ohki , Jun-ichi Hoshi , Takahiro Yamasaki
IPC分类号: C07D215/00 , C07C69/76 , C07C65/00 , C07C49/105
CPC分类号: C07C229/30 , C07C43/215 , C07C57/72 , C07C57/76 , C07C61/40 , C07C67/333 , C07C67/343 , C07C69/708 , C07C69/716 , C07C69/738 , C07C69/92 , C07C69/94 , C07C229/34 , C07D215/56
摘要: The present invention provides a compound useful as a synthetic intermediate for an anti-HIV agent having an integrase inhibitory activity, and a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate. Specifically, for example, a compound represented by the formula (2′): wherein R is a fluorine atom or a methoxy group, and R400 is a hydrogen atom or a C1-C4 alkyl group, or a salt thereof, and a production method thereof, and a production method of an anti-HIV agent using the synthetic intermediate.
摘要翻译: 本发明提供了可用作具有整合酶抑制活性的抗HIV剂的合成中间体的化合物及其制备方法,以及使用该合成中间体的抗HIV剂的制备方法。 具体而言,例如,式(2')表示的化合物或其盐,其中R为氟原子或甲氧基,R400为氢原子或C1-C4烷基, 以及使用该合成中间体的抗HIV剂的制造方法。
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公开(公告)号:US08442114B2
公开(公告)日:2013-05-14
申请号:US12923421
申请日:2010-09-21
申请人: Takahiro Yamasaki
发明人: Takahiro Yamasaki
IPC分类号: H04N7/12
CPC分类号: H04N19/115 , H04N19/395
摘要: A moving picture encoding apparatus divides a moving picture signal into key frames and non-key frames, encodes the key frames, predicts the non-key frames from the encoded key frames, determines a final encoding rate for each non-key frame, encodes each non-key frame, and outputs an error-correcting code at the final encoding rate as encoded data of the non-key frame. To determine the final encoding rate, the number of error-correcting bits needed to correct prediction errors is estimated by a first method and one or more second methods. The second methods are used to decide whether to use the number of bits estimated by the first method as the final encoding rate, or whether to supplement the estimated number of bits by adding an encoding rate correction. As a result, the encoding rate is not supplemented unnecessarily and the encoding efficiency is improved.
摘要翻译: 运动图像编码装置将运动图像信号划分成关键帧和非关键帧,对关键帧进行编码,从编码关键帧预测非关键帧,确定每个非关键帧的最终编码率,对每个非关键帧进行编码 非关键帧,并且以最终编码速率输出作为非关键帧的编码数据的纠错码。 为了确定最终编码速率,通过第一种方法和一种或多种第二种方法估计校正预测误差所需的纠错位数。 第二种方法用于决定是否使用由第一种方法估计的比特数作为最终编码率,或者是否通过添加编码率校正来补充估计的比特数。 结果,不需要补充编码率,提高编码效率。
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公开(公告)号:US08374255B2
公开(公告)日:2013-02-12
申请号:US12654335
申请日:2009-12-17
申请人: Takahiro Yamasaki
发明人: Takahiro Yamasaki
IPC分类号: H04N7/18
CPC分类号: H04N19/395 , H04N19/172 , H04N19/184 , H04N19/46
摘要: A moving picture sequence is divided into key frames, which are coded by a conventional method, and non-key frames, which are coded to obtain error-correcting information. The encoder and decoder independently generate predicted images for each non-key frame. The encoder compares its predicted image with the original non-key frame to estimate how much error-correcting information the decoder will need to decode the non-key frame by correcting prediction errors in the decoder's predicted image, and sends the decoder that amount of error-correcting information together with correlation information indicating how closely the predicted image and the original non-key frame are correlated. Before decoding the non-key frame, the decoder modifies the correlation information to compensate for differences in the prediction methods employed by the encoder and decoder. The modification enables the decoding process to converge faster.
摘要翻译: 运动图像序列被划分为通过常规方法编码的关键帧和被编码以获得纠错信息的非关键帧。 编码器和解码器独立地生成每个非关键帧的预测图像。 编码器将其预测图像与原始非关键帧进行比较,以通过校正解码器预测图像中的预测误差来估计解码器将需要解码非关键帧的纠错信息,并将解码器的误差量 - 校正信息以及指示预测图像和原始非关键帧相关联的相关信息。 在解码非关键帧之前,解码器修改相关信息以补偿编码器和解码器采用的预测方法的差异。 该修改使解码过程能够更快地收敛。
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公开(公告)号:US07604043B2
公开(公告)日:2009-10-20
申请号:US11662659
申请日:2005-09-09
IPC分类号: F24H3/06
CPC分类号: F24F1/0033 , F24F1/0007 , F24F1/0022 , F24F13/20 , F24F2001/0037 , F24F2013/088 , F24F2013/205
摘要: An air conditioner includes a unit casing, an impeller, a scroll casing, and a heat exchanger. The unit casing is partitioned by a partition member into a fan chamber and a heat exchanger chamber. The heat exchanger is disposed inside the heat exchanger chamber so as to face a scroll blowout opening in the scroll casing. The scroll casing is disposed inside the fan chamber. A wall section projects from a heat exchanger side of a flat plate section of the partition member and is disposed outside a scroll outlet section of the scroll casing.
摘要翻译: 空调机包括单元壳体,叶轮,涡旋壳体和热交换器。 单元壳体由分隔构件分隔成风扇室和热交换器室。 热交换器设置在热交换器室内,以面对涡旋壳体中的涡旋式吹出口。 涡旋壳体设置在风扇室内。 壁部从分隔构件的平板部的热交换器侧突出设置在涡旋壳体的涡旋出口部的外侧。
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公开(公告)号:US20090129919A1
公开(公告)日:2009-05-21
申请号:US12083002
申请日:2006-11-24
申请人: Takahiro Yamasaki , Akira Komatsu , Tooru Iwata
发明人: Takahiro Yamasaki , Akira Komatsu , Tooru Iwata
IPC分类号: F04D29/42
CPC分类号: F04D29/282 , F04D29/162 , F04D29/424
摘要: A multi-blade centrifugal fan for preventing circular flows in the end portions of an impeller in the axial direction is provided in a simple structure. The multi-blade centrifugal fan is formed of a fan casing 1 of a scroll type and a multi-blade centrifugal impeller 2. The fan casing 1 has a bellmouth 4 which becomes an air intake. The multi-blade centrifugal impeller 2 has a number of annularly arranged blades 6 inside the fan casing 1. The centrifugal impeller 2 draws in air through the intake 7, which faces the bellmouth 4, and blows out the air in the centrifugal direction through the blades 6. A retainer ring 10 is provided in an outer peripheral end portion of the impeller 2. A cylindrical body 11 is integrally provided in such a manner as to extend from the outer end of the retainer ring 10, so that circular flows toward the intake side are prevented in the end portions of the impeller 2.
摘要翻译: 以简单的结构提供用于防止叶轮在轴向端部的圆形流动的多叶片离心式风扇。 多叶片离心风扇由涡旋式风扇壳体1和多叶片离心式叶轮2形成。风扇壳体1具有形成进气口的喇叭口4。 多叶片离心式叶轮2在风扇壳体1内部具有多个环状排列的叶片6.离心式叶轮2通过面向喇叭口4的进气口7吸入空气,并通过离心式叶轮2离心吹出空气。 在叶轮2的外周端部设置有保持环10.圆筒体11一体地设置成从保持环10的外端延伸,使得圆形体朝向 吸入侧在叶轮2的端部被阻止。
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公开(公告)号:US06262402B1
公开(公告)日:2001-07-17
申请号:US09352164
申请日:1999-07-12
申请人: Shigeru Isoyama , Takeshi Hirabayashi , Hideyuki Nikaido , Toshiaki Amagasa , Nozomu Tamura , Takahiro Yamasaki , Masashi Osada , Hirosuke Yamada , Toshisada Takechi , Norio Takashima , Junzo Nitta , Shuji Amanuma , Kanji Hayashi , Akio Kuroda , Yoshiki Mito , Kunio Miyamoto , Kazuo Morimoto , Ikuo Wakamoto , Kazuya Tsurusaki , Hideo Sakamoto , Michio Hashimoto , Hiroyuki Nakano , Toshinobu Eguchi , Fumihiro Maeda
发明人: Shigeru Isoyama , Takeshi Hirabayashi , Hideyuki Nikaido , Toshiaki Amagasa , Nozomu Tamura , Takahiro Yamasaki , Masashi Osada , Hirosuke Yamada , Toshisada Takechi , Norio Takashima , Junzo Nitta , Shuji Amanuma , Kanji Hayashi , Akio Kuroda , Yoshiki Mito , Kunio Miyamoto , Kazuo Morimoto , Ikuo Wakamoto , Kazuya Tsurusaki , Hideo Sakamoto , Michio Hashimoto , Hiroyuki Nakano , Toshinobu Eguchi , Fumihiro Maeda
IPC分类号: H05B610
CPC分类号: B21B15/0085 , B21B1/26 , B23K13/015 , B23K13/02 , B23K2101/18
摘要: According to the invention, the rear end of a preceding metal piece and a front end of a succeeding metal piece are heated, pressed and joined prior to the finishing hot rolling. An alternating magnetic field running through the metal pieces in the thickness direction thereof is generated in an end region on opposed faces of the respective metal pieces to perform heating. Another alternating magnetic field whose direction is reverse with respect to that of the former alternating magnetic field is partially generated in the end region on the opposed faces of the metal pieces and in either a region where the metal pieces exist or a region outside width ends of the metal pieces. This assures a uniform heating of the end region on the opposed faces of the metal pieces over their full width to reliably join the both metal pieces to each other.
摘要翻译: 根据本发明,在精加工热轧之前,先前金属片的后端和后面的金属片的前端被加热,压制和接合。 在各个金属片的相对面上的端部区域中产生沿其厚度方向穿过金属片的交变磁场,以进行加热。 在金属片的相对面上的端部区域和金属片存在的区域或外侧宽度端部的区域中部分地产生相对于前者的交变磁场的方向相反的另一个交变磁场 金属件。 这确保了金属片的相对面上的端部区域在其全宽度上的均匀加热,以将两个金属片彼此可靠地接合。
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10.
公开(公告)号:US06218649B1
公开(公告)日:2001-04-17
申请号:US09352157
申请日:1999-07-12
申请人: Shigeru Isoyama , Takeshi Hirabayashi , Hideyuki Nikaido , Toshiaki Amagasa , Nozomu Tamura , Takahiro Yamasaki , Masashi Osada , Hirosuke Yamada , Toshisada Takechi , Norio Takashima , Junzo Nitta , Shuji Amanuma , Kanji Hayashi , Akio Kuroda , Yoshiki Mito , Kunio Miyamoto , Kazuo Morimoto , Ikuo Wakamoto , Kazuya Tsurusaki , Hideo Sakamoto , Michio Hashimoto , Hiroyuki Nakano , Toshinobu Eguchi , Fumihiro Maeda
发明人: Shigeru Isoyama , Takeshi Hirabayashi , Hideyuki Nikaido , Toshiaki Amagasa , Nozomu Tamura , Takahiro Yamasaki , Masashi Osada , Hirosuke Yamada , Toshisada Takechi , Norio Takashima , Junzo Nitta , Shuji Amanuma , Kanji Hayashi , Akio Kuroda , Yoshiki Mito , Kunio Miyamoto , Kazuo Morimoto , Ikuo Wakamoto , Kazuya Tsurusaki , Hideo Sakamoto , Michio Hashimoto , Hiroyuki Nakano , Toshinobu Eguchi , Fumihiro Maeda
IPC分类号: H05B610
CPC分类号: B21B15/0085 , B21B1/26 , B23K13/015 , B23K13/02 , B23K2101/18
摘要: Method and apparatus for joining metal pieces using induction heating. Metal pieces to be joined are placed end-to-end with a gap between them and induction heated in the thickness portion. To maximize speed and even heating edge-to-edge of the ends, members of a magnetic substance are provided in a gap between the inductor and the piece to be heated, thereby enhancing local heating effect by increasing magnetic flux density. Once heated, the ends are pressed together end-to-end for joining.
摘要翻译: 使用感应加热连接金属件的方法和装置。 要连接的金属片端对端放置,并在厚度部分进行感应加热。 为了最大化速度,甚至加热端部的边缘到边缘,磁性物质的构件设置在电感器和待加热件之间的间隙中,从而通过增加磁通密度来增强局部加热效果。 一旦被加热,端部端对端地被压在一起用于接合。
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