发明申请
- 专利标题: NITRATE ESTERS OF PIPERIDINES
- 专利标题(中): 硝酸酯系列
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申请号: US12310022申请日: 2007-08-07
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公开(公告)号: US20090325947A1公开(公告)日: 2009-12-31
- 发明人: Peter Herold , Robert Mah , Stefan Stutz , Vincenzo Tschinke , Isabelle Lyothier , Christoph Schumacher , Christiane Marti , Nathalie Jotterand
- 申请人: Peter Herold , Robert Mah , Stefan Stutz , Vincenzo Tschinke , Isabelle Lyothier , Christoph Schumacher , Christiane Marti , Nathalie Jotterand
- 优先权: CH01279/06 20060808
- 国际申请: PCT/EP2007/058207 WO 20070807
- 主分类号: A61K31/5377
- IPC分类号: A61K31/5377 ; C07D211/06 ; A61K31/445 ; C07D413/02
摘要:
The application relates to novel nitrate ester derivatives of substituted piperidines of the general formula (I), wherein R1, R2, R3, X, Y and Z0, and m, n, p and q have the meanings explained in more detail in the description, a process for their preparation and the use of these compounds as a curative agent in cardiovascular diseases, in particular in high blood pressure and vascular and organ damage accompanying high blood pressure.
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