- 专利标题: Promoters exhibiting endothelial cell specificity and methods of using same
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申请号: US12457200申请日: 2009-06-03
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公开(公告)号: US20090326052A1公开(公告)日: 2009-12-31
- 发明人: Dror Harats , Eyal Breitbart , Nira Bloom
- 申请人: Dror Harats , Eyal Breitbart , Nira Bloom
- 申请人地址: IL Or Yehuda
- 专利权人: Vascular Biogenics Ltd.
- 当前专利权人: Vascular Biogenics Ltd.
- 当前专利权人地址: IL Or Yehuda
- 主分类号: A61K31/713
- IPC分类号: A61K31/713 ; C12N15/85 ; C12N5/10 ; C12N5/00 ; A61P7/00
摘要:
An isolated polynucleotide functional as a promoter in eukaryotic cells is disclosed. The isolated polynucleotide includes an endothelial specific enhancer element as detailed herein. Further disclosed is a method of expressing a nucleic acid sequence of interest in endothelial cells.
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