Invention Application
- Patent Title: DIPEPTIDYL PEPTIDASE-IV INHIBITORS
- Patent Title (中): DIPEPTIDYL PEPTIDASE-IV抑制剂
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Application No.: US12492254Application Date: 2009-06-26
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Publication No.: US20100009961A1Publication Date: 2010-01-14
- Inventor: Heiko Kroth , Tim Feuerstein , Frank Richter , Jurgen Boer , Michael Essers , Bert Nolte , Matthias Schneider , Matthias Hochguertel , Fritz-Frieder Frickel , Arthur Taveras , Christoph Steeneck
- Applicant: Heiko Kroth , Tim Feuerstein , Frank Richter , Jurgen Boer , Michael Essers , Bert Nolte , Matthias Schneider , Matthias Hochguertel , Fritz-Frieder Frickel , Arthur Taveras , Christoph Steeneck
- Applicant Address: US MA Cambridge
- Assignee: Alantos Pharmaceuticals Holding, Inc.
- Current Assignee: Alantos Pharmaceuticals Holding, Inc.
- Current Assignee Address: US MA Cambridge
- Main IPC: A61K31/397
- IPC: A61K31/397 ; A61K31/5377 ; A61K31/41 ; A61K31/40 ; C07D413/14 ; C07D403/02 ; C07D207/00

Abstract:
The present invention relates generally to pyrrolidine and thiazolidine DPP-IV inhibitor compounds. The present invention also provides synthetic methods for preparation of such compounds, methods of inhibiting DPP-IV using such compounds and pharmaceutical formulations containing them for treatment of DPP-IV mediated diseases, in particular, Type-2 diabetes.
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