发明申请
- 专利标题： DIAGNOSIS OF INFLAMMATORY BOWEL DISEASE IN CHILDREN
- 专利标题（中）： 诊断儿童中的炎症性皮肤病
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申请号： US12529106申请日： 2008-03-06
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公开(公告)号： US20100015156A1公开(公告)日： 2010-01-21
- 发明人: Marla Dubinsky , Stephan R. Targan , Jerome I. Rotter
- 申请人： Marla Dubinsky , Stephan R. Targan , Jerome I. Rotter
- 申请人地址： US CA Los Angeles
- 专利权人： CEDARS-SINAI MEDICAL CENTER
- 当前专利权人： CEDARS-SINAI MEDICAL CENTER
- 当前专利权人地址： US CA Los Angeles
- 国际申请： PCT/US08/56103 WO 20080306
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C12Q1/68 ; A61P1/00 ; A61P29/00 ; A61P37/00
摘要：
This invention provides methods of diagnosing and predicting disease progression of Crohn's disease. In one embodiment, a method of the invention is practiced by determining the presence or absence of CARD15 variants R702W, G908R, and/or 1007insC in a pediatric individual. In another embodiment, a method of the invention is practiced by determining the presence or absence of anti-Cbir1, anti-OmpC, ASCA, and/or pANCA in a pediatric individual
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