Invention Application
- Patent Title: HEPARIN BINDING MOTIF AND USE THEREOF
- Patent Title (中): HEPARIN BINDING MOTIF及其使用
-
Application No.: US12545606Application Date: 2009-08-21
-
Publication No.: US20100016239A1Publication Date: 2010-01-21
- Inventor: Margaret Dah-Tsyr Chang , Tan-chi Fan , Shu-Chuan Lin
- Applicant: Margaret Dah-Tsyr Chang , Tan-chi Fan , Shu-Chuan Lin
- Applicant Address: TW Hsinchu
- Assignee: NATIONAL TSING HUA UNIVERSITY
- Current Assignee: NATIONAL TSING HUA UNIVERSITY
- Current Assignee Address: TW Hsinchu
- Main IPC: A61K38/08
- IPC: A61K38/08 ; C07K7/06 ; A61K38/10 ; A61P11/06
Abstract:
A method for reducing cytotoxicity of eosinophil derived toxins comprising administering to a subject an effective amount of heparin, heparan sulfate, a potent heparanase inhibitor or a polypeptide which has sequence as follows: BZBXBX, XBBBXXBX, XBBXBX, BBXXBBBXXBB, BXBBXB, XBBBXXBBBXXBBX, or TXXBXXTBXXXTBB, wherein X represents any amino acid, Z represents an aromatic amino acid, and B represents a basic amino acid and T represents a turn.
Information query
IPC分类:
