发明申请
- 专利标题： COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS
- 专利标题（中）： 作为蛋白激酶抑制剂的化合物和组合物
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申请号： US12444129申请日： 2007-09-24
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公开(公告)号： US20100029605A1公开(公告)日： 2010-02-04
- 发明人: Pamela Albaugh , Gregory S. Chopiuk , Qiang Ding , Shenlin Huang , Zuosheng Liu , Shifeng Pan , Pingda Ren , Xia Wang , Xing Wang , yongping Xie , Chengzhi Zhang , Qiong Zhang , Guobao Zhang , Daniel Poon , Paul Renhowe , Martin Sendzik
- 申请人： Pamela Albaugh , Gregory S. Chopiuk , Qiang Ding , Shenlin Huang , Zuosheng Liu , Shifeng Pan , Pingda Ren , Xia Wang , Xing Wang , yongping Xie , Chengzhi Zhang , Qiong Zhang , Guobao Zhang , Daniel Poon , Paul Renhowe , Martin Sendzik
- 申请人地址： BM Hamilton CH Basel
- 专利权人： IRM LLC ,Novartis AG
- 当前专利权人： IRM LLC ,Novartis AG
- 当前专利权人地址： BM Hamilton CH Basel
- 国际申请： PCT/US07/79340 WO 20070924
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; C07D413/14 ; C07D403/14 ; C07D403/04 ; A61K31/5377 ; A61K31/519
摘要：
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, ARG, BCR-Abl, BRK, EphB, Fms, Fyn, KDR, c-Kit, LCK, PDGF-R, b-Raf, c-Raf, SAPK2, Src, Tie2 and TrkB kinases.
公开/授权文献
- US08202876B2 Compounds and compositions as protein kinase inhibitors 公开/授权日：2012-06-19
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