发明申请
US20100062498A1 POLYPEPTIDE BEING CAPABLE OF INCREASING THE PRODUCTION OF L-METHIONINE, A MICROORGANISM THAT OVEREXPRESSES SAID POLYPEPTIDE AND A PROCESS OF PREPARING L-METHIONINE IN HIGH YIELD USING SAME
审中-公开
可以增加L-甲硫氨酸的生产的多肽，超过表达多肽的微生物和使用它们在高产量中制备L-甲硫氨酸的方法
- 专利标题： POLYPEPTIDE BEING CAPABLE OF INCREASING THE PRODUCTION OF L-METHIONINE, A MICROORGANISM THAT OVEREXPRESSES SAID POLYPEPTIDE AND A PROCESS OF PREPARING L-METHIONINE IN HIGH YIELD USING SAME
- 专利标题（中）： 可以增加L-甲硫氨酸的生产的多肽，超过表达多肽的微生物和使用它们在高产量中制备L-甲硫氨酸的方法
-
申请号： US12521541申请日： 2007-12-28
-
公开(公告)号： US20100062498A1公开(公告)日： 2010-03-11
- 发明人: Young Hoon Park , Kwang Myung Cho , So Young Kim , Yong Uk Shin , Hye Won Um
- 申请人： Young Hoon Park , Kwang Myung Cho , So Young Kim , Yong Uk Shin , Hye Won Um
- 申请人地址： KR SEOUL
- 专利权人： CJ CHEILJEDANG CORPORATION
- 当前专利权人： CJ CHEILJEDANG CORPORATION
- 当前专利权人地址： KR SEOUL
- 优先权： KR10-2006-0136919 20061228
- 国际申请： PCT/KR07/06979 WO 20071228
- 主分类号： C12P13/12
- IPC分类号： C12P13/12 ; C07K2/00 ; C07H21/04 ; C12N15/74 ; C12N1/21
摘要：
The present invention relates to a polypeptide capable of increasing the production of L-methionine in a microorganism. In particular, the present invention relates to an YgaZ and YgaH polypeptide or a complex thereof, referred to herein as YgaZH polypeptide, which are novel putative L-methionine exporters, polynucleotides encoding the same, a recombinant vector comprising the polynucleotide, a microorganism transformed with the recombinant vector, and a method for producing L-methionine and/or S-adenosyl-methionine, comprising the steps of culturing the transformed microorganism to produce L-methionine and/or S-adenosyl-methionine, and isolating L-methionine and/or S-adenosyl-methionine. The transformed microorganism of the present invention produces L-methionine in a high yield, thereby being used for medicinal and pharmaceutical industries and feed industry, in particular, animal feeds