发明申请
- 专利标题： Mercaptopurine derivatives and uses thereof
- 专利标题（中）： 巯基嘌呤衍生物及其用途
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申请号： US12529706申请日： 2008-03-02
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公开(公告)号： US20100069319A1公开(公告)日： 2010-03-18
- 发明人: Talia Miron , Aharon Rabinkov , David Mirelman , Meir Wilchek
- 申请人： Talia Miron , Aharon Rabinkov , David Mirelman , Meir Wilchek
- 国际申请： PCT/IL08/00268 WO 20080302
- 主分类号： A61K31/70
- IPC分类号： A61K31/70 ; C07D473/00 ; A61K31/52 ; C07H19/167
摘要：
The invention provides novel mercaptopurine derivatives, e.g., S-allylthio-6-mercaptopurine and S-allylthio-6-mercaptopurine 9-riboside, as well as pharmaceutical compositions thereof. These compounds are highly efficient anti-proliferative agents, thus can be useful for treatment of various diseases or disorders, in particular, proliferative, inflammatory, skin and immune diseases or disorders.
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