发明申请
- 专利标题： PROLYL HYDROXYLASE INHIBITORS
- 专利标题（中）： 丙基羟基酶抑制剂
-
申请号： US12305675申请日： 2007-06-22
-
公开(公告)号： US20100113444A1公开(公告)日： 2010-05-06
- 发明人: Kevin J. Duffy , Duke M. Fitch , Jian Jin , Ronggang Liu , Antony N. Shaw , Kenneth Wiggall
- 申请人： Kevin J. Duffy , Duke M. Fitch , Jian Jin , Ronggang Liu , Antony N. Shaw , Kenneth Wiggall
- 专利权人： Smithkline Beecham Corporation
- 当前专利权人： Smithkline Beecham Corporation
- 国际申请： PCT/US07/71854 WO 20070622
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; C07D239/60 ; C07D401/04 ; C07D405/04 ; C07D413/06 ; A61K31/505 ; A61K31/5377 ; A61P7/06 ; A61P9/00
摘要：
The invention described herein relates to certain pyrimidinetrione N-substituted glycine derivatives of formula (I), (I) which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.
公开/授权文献
- US08324208B2 Prolyl hydroxylase inhibitors 公开/授权日：2012-12-04