发明申请
- 专利标题： Modulators of ATP-Binding Cassette Transporters
- 专利标题（中）： ATP结合盒转运蛋白的调节剂
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申请号： US12544323申请日： 2009-08-20
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公开(公告)号： US20100144798A1公开(公告)日： 2010-06-10
- 发明人: Frederick F. VanGoor , Sara Sabina Hadida Ruah , Ashvani Kumar Singh , Eric R. Olson , Lewis Ray Makings , Jesus E. Gonzalez, III , James Arvid Rader , Fred Chambers, III , Mark Thomas Miller , Peter Diederik Jan Grootenhuis , Yahua Liu
- 申请人： Frederick F. VanGoor , Sara Sabina Hadida Ruah , Ashvani Kumar Singh , Eric R. Olson , Lewis Ray Makings , Jesus E. Gonzalez, III , James Arvid Rader , Fred Chambers, III , Mark Thomas Miller , Peter Diederik Jan Grootenhuis , Yahua Liu
- 申请人地址： US MA Cambridge
- 专利权人： VERTEX PHARMACEUTICALS INCORPORATED
- 当前专利权人： VERTEX PHARMACEUTICALS INCORPORATED
- 当前专利权人地址： US MA Cambridge
- 主分类号： A61K31/4439
- IPC分类号： A61K31/4439 ; A61K31/415 ; A61P1/12 ; A61P13/12 ; A61P15/10 ; A61P27/02 ; C12N5/00
摘要：
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
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