发明申请
- 专利标题: PURIFICATION OF TAXANES
- 专利标题(中): 净化紫杉醇
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申请号: US12705247申请日: 2010-02-12
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公开(公告)号: US20100145080A1公开(公告)日: 2010-06-10
- 发明人: James H. Johnson , T.G. Sambandam , Barry J. Hand , Christopher D. Howe , Roland R. Franke , Brian A. Bucher , John S. Juchum , Rex T. Gallagher , Marc A. Plante , Edward M. Desimone, III , Dong S. Yang
- 申请人: James H. Johnson , T.G. Sambandam , Barry J. Hand , Christopher D. Howe , Roland R. Franke , Brian A. Bucher , John S. Juchum , Rex T. Gallagher , Marc A. Plante , Edward M. Desimone, III , Dong S. Yang
- 申请人地址: US TX San Antonio
- 专利权人: Phyton Holdings LLC
- 当前专利权人: Phyton Holdings LLC
- 当前专利权人地址: US TX San Antonio
- 主分类号: C07D305/14
- IPC分类号: C07D305/14
摘要:
Disclosed is a method of crystallizing a taxane comprising combining the taxane and methylene chloride to obtain a solution and adding an anti-solvent to the solution to obtain a crystalline taxane, wherein the anti-solvent is selected from the group consisting of hexane and heptane.
公开/授权文献
- US08703982B2 Purification of taxanes 公开/授权日:2014-04-22
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