发明申请
- 专利标题: NOVEL COMPOUND HAVING GPR54 AGONISTIC ACTIVITY
- 专利标题(中): 具有GPR54激活活性的新化合物
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申请号: US12298200申请日: 2006-10-24
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公开(公告)号: US20100160241A1公开(公告)日: 2010-06-24
- 发明人: Nobutaka Fujii , Shinya Oishi , Kenji Tomita , Ayumu Niida
- 申请人: Nobutaka Fujii , Shinya Oishi , Kenji Tomita , Ayumu Niida
- 申请人地址: JP Kyoto
- 专利权人: Kyoto University
- 当前专利权人: Kyoto University
- 当前专利权人地址: JP Kyoto
- 优先权: JP2006-122305 20060426
- 国际申请: PCT/JP2006/321597 WO 20061024
- 主分类号: A61K38/08
- IPC分类号: A61K38/08 ; C07K5/103 ; C07K7/06 ; A61K38/07 ; A61P35/00
摘要:
The present invention provides a compound represented by the following formula (1); wherein R1 is an aryl group etc.; R2 is —CO—NH— etc.; R3 is a methyl group having an aromatic group or a cycloalkyl group; R4 is a hydrogen atom etc.; R5 is a methyl group having an aromatic group; and R6 is an amino group or an N-alkyl substituted amino group, having a low-molecular weight and a superior GPR54 agonist activity, and a pharmaceutical composition containing the compound.
公开/授权文献
- US08183212B2 Compound having GPR54 agonistic activity 公开/授权日:2012-05-22
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