发明申请
- 专利标题: MCP-1 SPLICE VARIANTS AND METHODS OF USING SAME
- 专利标题(中): MCP-1 SPLICE变量及其使用方法
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申请号: US12305953申请日: 2006-06-21
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公开(公告)号: US20100166733A1公开(公告)日: 2010-07-01
- 发明人: Zurit Levin , Amir Toporik , Michal Ayalon-Soffer , Iris Hecht , Merav Beiman , Dani Eshel , Tali Handelsman
- 申请人: Zurit Levin , Amir Toporik , Michal Ayalon-Soffer , Iris Hecht , Merav Beiman , Dani Eshel , Tali Handelsman
- 国际申请: PCT/IL2006/000710 WO 20060621
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07H21/00 ; C07K16/00 ; C12N15/74 ; C12N5/10 ; C12P21/00 ; A61K31/7088 ; A61K45/00 ; A61P3/10 ; A61P11/06 ; A61P11/08 ; A61P9/10 ; A61P21/00 ; A61P37/02
摘要:
Novel MCP-1 splice variant polypeptides and polynucleotides encoding same are provided. Also provided are pharmaceutical compositions comprising the splice variant polypeptides and polynucleotides, vectors and host cells comprising same. The compositions of the present invention are useful to treat various MCP-1 related disorders as well as for diagnosing, determining predisposition and/or prognosis of various disorders.
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