Invention Application
US20100183649A1 METHOD OF PRODUCING VIRUS-LIKE PARTICLES OF PICORNAVIRUS USING A SMALL-UBIQUITIN-RELATED FUSION PROTEIN EXPRESSION SYSTEM
有权
使用与小蛋白质相关的融合蛋白表达系统生产拟南芥的病毒颗粒的方法
- Patent Title: METHOD OF PRODUCING VIRUS-LIKE PARTICLES OF PICORNAVIRUS USING A SMALL-UBIQUITIN-RELATED FUSION PROTEIN EXPRESSION SYSTEM
- Patent Title (中): 使用与小蛋白质相关的融合蛋白表达系统生产拟南芥的病毒颗粒的方法
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Application No.: US12683568Application Date: 2010-01-07
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Publication No.: US20100183649A1Publication Date: 2010-07-22
- Inventor: Ting-Fang Wang , Shu-Mei Liang
- Applicant: Ting-Fang Wang , Shu-Mei Liang
- Applicant Address: TW Taipei
- Assignee: Academia Sinica
- Current Assignee: Academia Sinica
- Current Assignee Address: TW Taipei
- Main IPC: A61K39/135
- IPC: A61K39/135 ; C12P21/00 ; C12P21/06 ; A61P31/12 ; C12N1/20
Abstract:
A method for producing picornaviral capsid protein complexes (e.g., picornavirus like particles) in E. coli using a small-ubiquitin-related fusion protein expression system and an E. coli strain used in practicing this method. Also disclosed is use of the picornaviral capsid protein complexes like thus prepared for eliciting immune responses.
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