- 专利标题: APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
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申请号: US12689133申请日: 2010-01-18
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公开(公告)号: US20100184766A1公开(公告)日: 2010-07-22
- 发明人: Aaron R. Kunzer , Steven W. Elmore , Laura A. Hexamer , Cheol-Min Park , Andrew J. Souers , Gerard M. Sullivan , Gary T. Wang , Xilu Wang , Michael D. Wendt
- 申请人: Aaron R. Kunzer , Steven W. Elmore , Laura A. Hexamer , Cheol-Min Park , Andrew J. Souers , Gerard M. Sullivan , Gary T. Wang , Xilu Wang , Michael D. Wendt
- 申请人地址: US IL Abbott Park
- 专利权人: ABBOTT LABORATORIES
- 当前专利权人: ABBOTT LABORATORIES
- 当前专利权人地址: US IL Abbott Park
- 主分类号: A61K31/496
- IPC分类号: A61K31/496 ; C07D409/02 ; C07D409/14 ; C07D417/02 ; C07D413/02 ; A61K31/4535 ; A61K31/5377 ; A61P35/00 ; A61P35/02
摘要:
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.