发明申请
US20100189682A1 Biologically active proteins having increased In Vivo and/or In Vitro stability
审中-公开
具有增加体内和/或体外稳定性的生物活性蛋白质
- 专利标题： Biologically active proteins having increased In Vivo and/or In Vitro stability
- 专利标题（中）： 具有增加体内和/或体外稳定性的生物活性蛋白质
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申请号： US12634556申请日： 2009-12-09
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公开(公告)号： US20100189682A1公开(公告)日： 2010-07-29
- 发明人: Volker Schellenberger , Willem P. Stemmer , Chia-wei Wang , Michael D. Scholle , Mikhail Popkov , Nathaniel C. Gordon , Andreas Crameri
- 申请人： Volker Schellenberger , Willem P. Stemmer , Chia-wei Wang , Michael D. Scholle , Mikhail Popkov , Nathaniel C. Gordon , Andreas Crameri
- 主分类号： A61K38/20
- IPC分类号： A61K38/20 ; C07K14/00 ; A61K38/16 ; C07K16/00 ; A61K39/395 ; C07K14/52 ; C07K14/475 ; C07H21/04 ; A61P37/00 ; A61P35/00 ; A61P3/10 ; A61P9/10 ; A61P13/12 ; A61P7/02 ; A61P29/00 ; A61K38/21 ; C12N9/00 ; C12N15/63 ; C12N5/10 ; C12P21/02
摘要：
The present invention provides unstructured recombinant polymers (URPs) and proteins containing one or more of the URPs. The present invention also provides microproteins, toxins and other related proteinaceous entities, as well as genetic packages displaying these entities. The present invention also provides recombinant polypeptides including vectors encoding the subject proteinaceous entities, as well as host cells comprising the vectors. The subject compositions have a variety of utilities including a range of pharmaceutical applications.
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