发明申请
- 专利标题： NOVEL CURCUMIN ANALOGUES AND USES THEREOF
- 专利标题（中）： 新型CURCUMIN类似物及其用途
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申请号： US12758462申请日： 2010-04-12
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公开(公告)号： US20100197784A1公开(公告)日： 2010-08-05
- 发明人: Kuo-Hsiung Lee , Li Lin , Charles C-Y Shih , Ching-Yuan Su , Junko Ishida , Hironori Ohtsu , Hui-Kang Wang , Hideji Itokawa , Chawnshang Chang
- 申请人： Kuo-Hsiung Lee , Li Lin , Charles C-Y Shih , Ching-Yuan Su , Junko Ishida , Hironori Ohtsu , Hui-Kang Wang , Hideji Itokawa , Chawnshang Chang
- 申请人地址： US NC Chapel Hill US NY Rochester US CA San Diego
- 专利权人： The University of North Carlina at Chapel Hill,The University of Rochester Medical Center,Androscience Corporation
- 当前专利权人： The University of North Carlina at Chapel Hill,The University of Rochester Medical Center,Androscience Corporation
- 当前专利权人地址： US NC Chapel Hill US NY Rochester US CA San Diego
- 主分类号： A61K31/12
- IPC分类号： A61K31/12 ; C12N5/00 ; A61K31/215 ; A61P17/10 ; A61P35/02 ; A61P35/00
摘要：
The present invention relates to compounds capable of acting as androgen receptor antagonists, pharmaceutical formulations containing the same, and methods of use thereof. Such uses include, but are not limited to, use as antitumor agents, particularly for the treatment of cancers such as colon, skin and prostate cancer and to induce androgen receptor antagonist activity in a subject afflicted with an androgen-related affliction. Examples of androgen-related afflictions include, but are not limited to, baldness, hirsutism, behavioral disorders, acne, and uninhibited spermatogenesis wherein inhibition of spermatogenesis is so desired.
公开/授权文献
- US08198323B2 Curcumin analogues and uses thereof 公开/授权日：2012-06-12
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