发明申请
- 专利标题： RECOMBINANT TRANSFERRIN MUTANTS
- 专利标题（中）： 重组转铁蛋白
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申请号： US12664454申请日： 2008-06-13
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公开(公告)号： US20100222267A1公开(公告)日： 2010-09-02
- 发明人: Christopher John Arthur Finnis , Darrell Sleep , Joanna Hay
- 申请人： Christopher John Arthur Finnis , Darrell Sleep , Joanna Hay
- 申请人地址： DK Bagsvaerd
- 专利权人： Novozymes Biopharma UK Limited.
- 当前专利权人： Novozymes Biopharma UK Limited.
- 当前专利权人地址： DK Bagsvaerd
- 优先权： EP0711424.2 20070613
- 国际申请： PCT/EP2008/057508 WO 20080613
- 主分类号： A61K38/40
- IPC分类号： A61K38/40 ; C07K14/79 ; C07H21/04 ; C12N15/63 ; C12P21/06 ; C12N5/00 ; C12N5/02
摘要：
The present invention provides a recombinant protein comprising the sequence of a transferrin mutant, wherein Ser415 is mutated to an amino acid which does not allow glycosylation at Asn413 and/or wherein Thr613 is mutated to an amino acid which does not allow glycosylation as Asn611. It also provides polynucleotides encoding the same and methods of making and using said recombinant protein.
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