- 专利标题： POLYMERIC DELIVERY FORMULATIONS OF LEUPROLIDE WITH IMPROVED EFFICACY
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申请号： US12784343申请日： 2010-05-20
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公开(公告)号： US20100234305A1公开(公告)日： 2010-09-16
- 发明人: Richard L. Dunn , John Steven Garrett , Harish Ravivarapu , Bhagya L. Chandrashekar
- 申请人： Richard L. Dunn , John Steven Garrett , Harish Ravivarapu , Bhagya L. Chandrashekar
- 申请人地址： US DE Willmington
- 专利权人： QLT USA, INC.
- 当前专利权人： QLT USA, INC.
- 当前专利权人地址： US DE Willmington
- 主分类号： A61K38/08
- IPC分类号： A61K38/08 ; A61P5/24
摘要：
The present invention is directed to a flowable composition that is suitable for use as a controlled release implant. The flowable composition includes a biodegradable thermoplastic polyester that is at least substantially insoluble in aqueous medium or body fluid. The flowable composition also includes a biocompatible polar aprotic solvent. The biocompatible polar aprotic solvent is miscible to dispersible in aqueous medium or body fluid. The flowable composition also includes leuprolide acetate.
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