发明申请
- 专利标题： COMPOUND AND USE THEREOF IN THE TREATMENT OF AMYLOIDOSIS
- 专利标题（中）： 化合物及其在治疗淀粉样变性中的应用
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申请号： US12728361申请日： 2010-03-22
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公开(公告)号： US20100249233A1公开(公告)日： 2010-09-30
- 发明人: Mark Brian PEPYS , Steven Victor Ley , Angus John Morrison , Vittorio Bellotti , Stephen Wood , Simon Kolstoe , Martin Smith
- 申请人： Mark Brian PEPYS , Steven Victor Ley , Angus John Morrison , Vittorio Bellotti , Stephen Wood , Simon Kolstoe , Martin Smith
- 优先权： GB0718718.0 20070925
- 主分类号： A61K31/196
- IPC分类号： A61K31/196 ; C07C229/58 ; A61P43/00
摘要：
The present invention relates to compounds of formula (I) for stabilizing the tetrameric form of transthyretin, compounds for use in the treatment or prevention of amyloidosis, and agents and medicaments comprising such compounds. wherein X, Y, R1, R2, R3, R4, m, n, p, q, and the linker are as defined herein.
公开/授权文献
- US08236984B2 Compound and use thereof in the treatment of amyloidosis 公开/授权日：2012-08-07
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