摘要:
The present invention relates to compounds of formula (I) for stabilizing the tetrameric form of transthyretin, compounds for use in the treatment or prevention of amyloidosis, and agents and medicaments comprising such compounds. wherein X, Y, R1, R2, R3, R4, m, n, p, q, and the linker are as defined herein.
摘要:
The present invention relates to compounds of formula (I) for stabilizing the tetrameric form of transthyretin, compounds for use in the treatment or prevention of amyloidosis, and agents and medicaments comprising such compounds. wherein X, Y, R1, R2, R3, R4, m, n, p, q, and the linker are as defined herein.
摘要:
A module (38), a terminal (12) including the module, and a system (10) including the terminal (12), are described. The module may be a printer module (38) comprising a print engine (60), a microcontroller (62), and a wireless receiver (66), such as a wireless modem, so that the module (38) is operable to receive data from a remote server (18) and to print the received data. The module (38) also includes a coupler (70 or 270) for directing data received from the wireless modem (66) to the microcontroller (62) and for directing data from the terminal (12) to the microcontroller (62). A method of printing tickets at a terminal (12) and a method of retro-fitting a self-service terminal (12) are also described.
摘要:
To provide a catalyst for synthesis reaction which can achieve good yield in the Sonogashira reaction and also can be recovered after the reaction, and a method for synthesizing a compound in which the catalyst for synthesis reaction is used, a perovskite-type composite oxide containing palladium is used as the catalyst for synthesis reaction in the Sonogashira reaction represented by the following reaction scheme (1): R1—X+HC≡CR2→R1C≡CR2 (1)
摘要翻译:为了提供合成反应的催化剂,其能够在Sonogashira反应中获得良好的产率,并且也可以在反应后回收,以及合成其中使用合成反应的催化剂的化合物的方法,含有钯的钙钛矿型复合氧化物 用作由以下反应方案(1)表示的Sonogashira反应中的合成反应的催化剂:<?in-line-formula description =“In-line formula”end =“lead”?> R&lt; 1& / SUB + -X +HC≡CR2 - > R 1C≡CR2(1)<β在线公式描述 =“内联公式”end =“tail”?>
摘要:
The present invention relates to methods for isolating and storing, nucleic acid from a sample containing nucleic acid, such as a cell sample or cell lysate. The nucleic acid is isolated on a solid phase medium, which is then dried, and which can be stored efficiently, such as at room temperature, in columns, tubes, and microwell plates having a wide variety of filters and other solid phase media, for extended periods of time, including days, weeks, and months. The invention provides methods for isolating and storing nucleic acid from a sample by applying the sample to a solid phase medium, retaining the cells, lysing the cellular retentate, drying the medium and retaining the nucleic acid, storing the nucleic acid for extended periods of time at room temperature and humidity, and optionally eluting the nucleic acid. The invention provides methods for storing nucleic acid-containing samples on a wide range of solid phase media in many types of tubes, columns, or multiwell plates, many of which are commercial available.
摘要:
Previous MIMO systems have used spatially diverse antenna elements in order not to reduce the number of orthogonal channels that can be realized. The present invention recognizes that this leads to large antenna sizes, as compared to multiple beam antenna systems which use closely spaced antenna elements. In order to provide a compact antenna unit, while still allowing a MIMO system to be exploited, the present invention recognizes that polarization diversity only can be used in a MIMO system without the need for spatially diverse antenna elements. Closely spaced antenna elements are used and this enables a compact MIMO antenna unit to be provided. In addition, such MIMO systems with polarization diversity but no spatial diversity can advantageously be used in line of sight situations and also combined with multi-beam antenna systems to further increase capacity.
摘要:
The present invention provides for device for obtaining and storing genetic material. The device has a support and a head portion. The head portion is composed of a solid matrix for sorbing genetic material and a preserving mechanism for the protection of genetic material from degradation. Additionally, the present invention provides for a method of storing a sample of genetic material onto the swab device. In the preferred embodiment, the present invention utilizes polyester material as the solid matrix.
摘要:
A customer's mobile device comprises a camera and a processor. The camera is used to scan a two-dimensional barcode which has encoded within it transaction details and ancillary information relating to purchases made by a customer in their receipted transaction.
摘要:
A method of managing lost returns in a wellbore is disclosed. The method includes contacting a filter cake with a treating fluid to remove metallic weighting agents from the filter cake, wherein the filter cake is disposed on a face of a formation fracture in the wellbore. The method also includes contacting the filter cake with a proppant slurry, wherein the proppant slurry contacts the filter cake concurrently with the treating fluid or after the treating fluid contacts the filter cake. This method may include increasing the filter cake permeability and may utilize a barite removal agent, such as a chelation agent. At least one related wellbore management method is disclosed, which provides for creating a fracture in the wellbore and propping open the fracture to increase wellbore integrity to utilize higher weight drilling fluids and prevent fractures from forming further down the wellbore.
摘要:
The invention is directed to methods and apparatus for transmitting data between a first node and a second node in a communications network, for example a wireless network. The method comprises the steps of selecting a transmission channel from a predetermined set of transmission channels according to probability information and transmitting data using the selected channel. The probability information is based on a determination of a characteristic of previous transmissions using each of said set of channels. The invention is also directed to a method of selecting a channel at a node in a communications network for communication with a second node.