发明申请
- 专利标题： PEPTIDES WITH CAPACITY TO BIND TO SCURFIN AND APPLICATIONS
- 专利标题（中）： 具有能力的蛋白质和蛋白质的应用
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申请号： US12743616申请日： 2008-11-14
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公开(公告)号： US20100267623A1公开(公告)日： 2010-10-21
- 发明人: Inés Noelia Casares Lagar , Francisco Borras Cuesta , Pablo Sarobe Ugarriza , Jesús Prieto Valtueña , Juan José Lasarte Sagastibelza
- 申请人： Inés Noelia Casares Lagar , Francisco Borras Cuesta , Pablo Sarobe Ugarriza , Jesús Prieto Valtueña , Juan José Lasarte Sagastibelza
- 申请人地址： ES Cizur Mayor - Navarra
- 专利权人： PROYECTO DE BIOMEDICINA CIMA, S.L.
- 当前专利权人： PROYECTO DE BIOMEDICINA CIMA, S.L.
- 当前专利权人地址： ES Cizur Mayor - Navarra
- 优先权： ESP200703052 20071119
- 国际申请： PCT/ES2008/000716 WO 20081114
- 主分类号： A61K38/10
- IPC分类号： A61K38/10 ; C07K7/08 ; C07K14/00 ; A61P35/00 ; A61P31/04 ; A61P31/10 ; A61P31/12 ; A61P33/02 ; C07H21/04 ; C12N15/63 ; C12N1/00 ; C12P21/06
摘要：
The invention relates to peptides of general formula (I), wherein X is absent or X is present and is X14 or X14-X15, wherein X14 and X15, independently from one another, represent an amino acid; their functional variants and fragments, and their pharmaceutically acceptable salts, having the capacity to bind to scurfin and inhibit its biological activity, therefore they regulate or block the activity of regulatory T (Treg) lymphocytes. They are applicable in the treatment of infectious and neoplastic diseases. Arg-Asp-Phe-Gln-Ser-Phe-Arg-Lys-Met-Trp-Pro-Phe- Phe-X (I)
公开/授权文献
- US08524860B2 Peptides with capacity to bind to scurfin and applications 公开/授权日：2013-09-03
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